Evidence map›Paper›PMID 24362759›Full record

ArticleNature neuroscience2014

An electroconvulsive therapy procedure impairs reconsolidation of episodic memories in humans.

Marijn C W Kroes, Indira Tendolkar, Guido A van Wingen, Jeroen A van Waarde, Bryan A Strange, Guillén Fernández

Abstract read
PubMed Publisher
In one paragraph

Article in Nature neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed.

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  5. Intrusions in episodic memory: reconsolidation or interference?Learning & memory (Cold Spring Harbor, N.Y.) · 2017
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  6. How Administration of the Beta-Blocker Propranolol Before Extinction can Prevent the Return of Fear.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2016
    Trial
  7. Article
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  17. Selectively Interfering With Intrusive but Not Voluntary Memories of a Trauma Film: Accounting for the Role of Associative Memory.Clinical psychological science : a journal of the Association for Psychological Science · 2021
    Article
  18. Suppressing the Morning Cortisol Rise After Memory Reactivation at 4 A.M. enhances Episodic Memory Reconsolidation in Humans.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marijn C W KroesDonders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands.
Indira Tendolkar1] Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands. [2] Department of Psychiatry, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. [3] Department of Psychiatry and Psychotherapy, University Hospital Essen, Essen, Germany.
Guido A van Wingen1] Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands. [2] Department of Psychiatry, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
Jeroen A van WaardeDepartment of Psychiatry, Rijnstate Hospital, Arnhem, The Netherlands.
Bryan A StrangeLaboratory for Clinical Neuroscience, Centre for Biomedical Technology, UPM, Madrid, Spain.
Guillén Fernández1] Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands. [2] Department of Cognitive Neuroscience, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite accumulating evidence for a reconsolidation process in animals, support in humans, especially for episodic memory, is limited. Using a within-subjects manipulation, we found that a single application of electroconvulsive therapy following memory reactivation in patients with unipolar depression disrupted reactivated, but not non-reactivated, memories for an emotional episode in a time-dependent manner. Our results provide evidence for reconsolidation of emotional episodic memories in humans.

Indexed as

Memory, EpisodicAdultAnalysis of VarianceChoice BehaviorDepressive DisorderElectroconvulsive TherapyFemaleFollow-Up StudiesHumansLearningMaleMathematicsMemory DisordersMiddle AgedRetrospective StudiesTime Factors

Identifiers

PMID24362759

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.