Evidence map›Paper›PMID 24361633›Full record

ReviewAIDS (London, England)2013

Beyond early infant diagnosis: case finding strategies for identification of HIV-infected infants and children.

Saeed Ahmed, Maria H Kim, Nandita Sugandhi, B Ryan Phelps, Rachael Sabelli, Mamadou O Diallo, Paul Young, Dana Duncan, Scott E Kellerman, Child Survival Working Group of the Interagency Task Team on the Prevention and Treatment of HIV infection in Pregnant Women, Mothers and Children

Abstract readReview
In one paragraph

Review in AIDS (London, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Financial Incentives for Pediatric HIV Testing in Kenya.The Pediatric infectious disease journal · 2018
    Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Cytomegalovirus Viremia and Clinical Outcomes in Kenyan Children Diagnosed With Human Immunodeficiency Virus (HIV) in Hospital.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Observational
  11. Article
  12. Article
  13. Observational
  14. Article
  15. Article
  16. Observational
  17. Article
  18. Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Saeed AhmedaBaylor College of Medicine Clinical Centre of Excellence, Lilongwe, Malawi bClinton Health Access Initiative, New York, New York cUnited States Agency for International Development, Washington, DC, USA dCenters for Disease Control and Prevention, Atlanta, Georgia eManagement Sciences for Health, Washington, DC, USA.
Maria H Kim
Nandita Sugandhi
B Ryan Phelps
Rachael Sabelli
Mamadou O Diallo
Paul Young
Dana Duncan
Scott E Kellerman
Child Survival Working Group of the Interagency Task Team on the Prevention and Treatment of HIV infection in Pregnant Women, Mothers and Children

Funding

Virology CoreP30AI036211 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI KOZINETZ, CLAUDIA A. · 1994 to 2015
$21.7M
Improving prevention of mother-to-child HIV transmission outcomes in MalawiK01TW009644 · FIC · BAYLOR COLLEGE OF MEDICINE · PI KIM, MARIA HYOUN · 2013 to 2017
$663k
FIC NIH HHS K01 TW009644NIAID NIH HHS P30 AI036211
6 · The paper itself

Abstract

There are 3.4 million children infected with HIV worldwide, with up to 2.6 million eligible for treatment under current guidelines. However, roughly 70% of infected children are not receiving live-saving HIV care and treatment. Strengthening case finding through improved diagnosis strategies, and actively linking identified HIV-infected children to care and treatment is essential to ensuring that these children benefit from the care and treatment available to them. Without attention or advocacy, the majority of these children will remain undiagnosed and die from complications of HIV. In this article, we summarize the challenges of identifying HIV-infected infants and children, review currently available evidence and guidance, describe promising new strategies for case finding, and make recommendations for future research and interventions to improve identification of HIV-infected infants and children.

Indexed as

HIV InfectionsAdolescentAdultChildChild Health ServicesChild, OrphanedChild, PreschoolEarly DiagnosisFemaleHealth Services AccessibilityHumansImmunization ProgramsInfantInfant, NewbornInfectious Disease Transmission, VerticalMale

Identifiers

PMID24361633
PMCPMC4122794

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.