Evidence map›Paper›PMID 24361632›Full record

ReviewAIDS (London, England)2013

Beyond prevention of mother-to-child transmission: keeping HIV-exposed and HIV-positive children healthy and alive.

Scott E Kellerman, Saeed Ahmed, Theresa Feeley-Summerl, Jonathan Jay, Maria Kim, B Ryan Phelps, Nandita Sugandhi, Erik Schouten, Mike Tolle, Fatima Tsiouris and 1 more

Abstract readHistorical ArticleReview
In one paragraph

Review in AIDS (London, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Trial
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  8. Review
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  17. Article
  18. Brief Report: Impact of Option B+ on the Infant PMTCT Cascade in Lilongwe, Malawi.Journal of acquired immune deficiency syndromes (1999) · 2015
    Observational
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Scott E KellermanaManagement Sciences for Health, Washington, DC bBaylor College of Medicine, Texas Childrens Hospital, Houston, Texas cManagement Sciences for Health, Cambridge, Massachusetts dOffice of HIV/AIDS, USAID, Washington, DC eClinton Health Access Initiative, New York City, New York, USA fManagement Sciences for Health, Lilongwe, Malawi gICAP - Columbia University, Mailman School of Public Health, New York, New York, USA.
Saeed Ahmed
Theresa Feeley-Summerl
Jonathan Jay
Maria Kim
B Ryan Phelps
Nandita Sugandhi
Erik Schouten
Mike Tolle
Fatima Tsiouris
Child Survival Working Group of the Interagency Task Team on the Prevention and Treatment of HIV infection in Pregnant Women, Mothers and Children

Funding

Virology CoreP30AI036211 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI KOZINETZ, CLAUDIA A. · 1994 to 2015
$21.7M
Improving prevention of mother-to-child HIV transmission outcomes in MalawiK01TW009644 · FIC · BAYLOR COLLEGE OF MEDICINE · PI KIM, MARIA HYOUN · 2013 to 2017
$663k
FIC NIH HHS K01 TW009644NIAID NIH HHS P30 AI036211
6 · The paper itself

Abstract

In 2011, Joint United Nations Programme on HIV/AIDS announced a plan to eliminate new HIV infections among children by 2015. This increased focus on the elimination of maternal to child transmission (MTCT) is most welcome but is insufficient, as access to prevention of MTCT (PMTCT) programming is neither uniform nor universal. A new and more expansive agenda must be articulated to ensure that those infants and children who will never feel the impact of the current elimination agenda are reached and linked to appropriate care and treatment. This agenda must addresses challenges around both reducing vertical transmission through PMTCT and ensuring access to appropriate HIV testing, care, and treatment for all affected children who were never able to access PMTCT programming. Option B+, or universal test and treat for HIV-infected pregnant women is an excellent start, but it may be time to rethink our current approaches to delivering PMTCT services. New strategies will reduce vertical transmission to less than 1% for those mother-infant pairs who can access them allowing for the contemplation of not just PMTCT, but actual elimination of MTCT. But expanded thinking is needed to ensure elimination of pediatric HIV.

Indexed as

AdultAnti-HIV AgentsChildDisease-Free SurvivalFemaleGlobal HealthHistory, 20th CenturyHistory, 21st CenturyHIV InfectionsHumansInfectious Disease Transmission, VerticalLost to Follow-UpMalePregnancyPregnancy Complications, InfectiousPreventive Health ServicesAnti-HIV Agents

Identifiers

PMID24361632
PMCPMC4087192

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.