Evidence map›Paper›PMID 24361304›Full record

ArticleSchizophrenia research2014

Response selection impairment in schizophrenia transcends sensory and motor modalities.

Neil D Woodward, Brittney Duffy, Haleh Karbasforoushan

Open access · greenAbstract read
In one paragraph

Article in Schizophrenia research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Neil D WoodwardPsychotic Disorders and Psychiatric Neuroimaging Programs, Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, TN, USA.
Brittney DuffyPsychotic Disorders and Psychiatric Neuroimaging Programs, Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, TN, USA.
Haleh KarbasforoushanPsychotic Disorders and Psychiatric Neuroimaging Programs, Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, TN, USA.
Vanderbilt Psychiatric Hospital · USVanderbilt University · US

Funding

Cognitive neuroscience of processing speed dysfunction in schizophreniaR21MH096177 · NIMH · VANDERBILT UNIVERSITY · PI WOODWARD, NEIL D. · 2012 to 2013
$420k
NIMH NIH HHS 5R21MH096177NIMH NIH HHS R21 MH096177
6 · The paper itself

Abstract

Response selection dysfunction contributes to processing speed impairment in schizophrenia. However, it is unclear if response selection impairment transcends sensory and motor modalities or is modality specific. To address this question, healthy subjects and individuals with schizophrenia completed reaction time (RT) experiments with different combinations of sensory cues (i.e. visual, auditory) and motor response (i.e. manual, vocal). We found that response selection impairment in schizophrenia was present regardless of the sensory and motor modality of the tasks and correlated with performance on neuropsychological tests of processing speed. These results implicate dysfunction of amodal response selection brain regions in schizophrenia. Interventions that reduce the length of response selection stage processing may improve processing speed in schizophrenia.

Indexed as

Schizophrenic PsychologyAcoustic StimulationAdultChoice BehaviorCognition DisordersCuesFemaleHumansIntelligence TestsMaleMiddle AgedNeuropsychological TestsPhotic StimulationPsychomotor PerformanceReaction TimeSchizophreniaMotorProcessing speedResponse selectionSchizophreniaSensory

Identifiers

PMID24361304
PMCPMC3925400
OpenAlexW1982239333

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.