Evidence map›Paper›PMID 24359585›Full record

ArticleBreast cancer research : BCR2013

Cancer dormancy: time to explore its clinical relevance.

Miodrag Gužvić, Christoph A Klein

Abstract readComment
In one paragraph

Article in Breast cancer research : BCR, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Dormancy and NKG2D system in brain metastases: Analysis of immunogenicity.International journal of molecular medicine · 2020
    Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Miodrag Gužvić
Christoph A Klein

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dormant disseminated cancer cells, arrested and nonproliferating, are "good" cancer cells because there is no need to worry unless they resume growth. The mechanisms by which dormant disseminated cancer cells are put to sleep at distant sites and re-awakened are poorly understood. Moreover, it is not clear whether re-awakened cancer cells have a role in disease courses. Cyrus Ghajar and colleagues identified a mechanism of dormancy and growth resumption that might become important when more closely linked to clinical reality.

Indexed as

Neovascularization, PathologicAnimalsBone Marrow NeoplasmsBrain NeoplasmsBreast NeoplasmsEndothelium, VascularFemaleHumansLung NeoplasmsNeoplasm, ResidualPericytes

Identifiers

PMID24359585
PMCPMC3979111

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.