ArticleF1000Research2012
Is the pan-genome also a pan-selectome?
Article in F1000Research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
23 citing papers in PubMed.
- Article
- High genomic differentiation and limited gene flow indicate recent cryptic speciation within the genusFrontiers in microbiology · 2022Article
- Disentangling the impact of environmental and phylogenetic constraints on prokaryotic within-species diversity.The ISME journal · 2020Article
- Estimating Pangenomes with Roary.Molecular biology and evolution · 2020Article
- Article
- Multidrug resistant pathogens respond differently to the presence of co-pathogen, commensal, probiotic and host cells.Scientific reports · 2018Article
- The nucleotide composition of microbial genomes indicates differential patterns of selection on core and accessory genomes.BMC genomics · 2017Article
- Microdiversification of a Pelagic Polynucleobacter Species Is Mainly Driven by Acquisition of Genomic Islands from a Partially Interspecific Gene Pool.Applied and environmental microbiology · 2017Article
- Pangenome Evolution in the Marine Bacterium Alteromonas.Genome biology and evolution · 2016Article
- Article
- Diversity of the cell-wall associated genomic island of the archaeon Haloquadratum walsbyi.BMC genomics · 2015Article
- A novel method of consensus pan-chromosome assembly and large-scale comparative analysis reveal the highly flexible pan-genome of Acinetobacter baumannii.Genome biology · 2015Article
- Prochlorococcus: the structure and function of collective diversity.Nature reviews. Microbiology · 2015Review
- Genome dynamics and evolution of Salmonella Typhi strains from the typhoid-endemic zones.Scientific reports · 2014Article
- Leptospiral pathogenomics.Pathogens (Basel, Switzerland) · 2014Review
- Homologous recombination is involved in the diversity of replacement flexible genomic islands in aquatic prokaryotes.Frontiers in genetics · 2014Article
- Tales from a thousand and one phages.Bacteriophage · 2014Article
- Evidence for metaviromic islands in marine phages.Frontiers in microbiology · 2014Article
- Genomes of "Spiribacter", a streamlined, successful halophilic bacterium.BMC genomics · 2013Article
- Genomic diversity of "deep ecotype" Alteromonas macleodii isolates: evidence for Pan-Mediterranean clonal frames.Genome biology and evolution · 2013Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The comparative genomics of prokaryotes has shown the presence of conserved regions containing highly similar genes (the 'core genome') and other regions that vary in gene content (the 'flexible' regions). A significant part of the latter is involved in surface structures that are phage recognition targets. Another sizeable part provides for differences in niche exploitation. Metagenomic data indicates that natural populations of prokaryotes are composed of assemblages of clonal lineages or "meta-clones" that share a core of genes but contain a high diversity by varying the flexible component. This meta-clonal diversity is maintained by a collection of phages that equalize the populations by preventing any individual clonal lineage from hoarding common resources. Thus, this polyclonal assemblage and the phages preying upon them constitute natural selection units.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.