ReviewCurrent opinion in immunology2013
A systems framework for vaccine design.
Review in Current opinion in immunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- A Systems Vaccinology Approach Reveals the Mechanisms of Immunogenic Responses to Hantavax Vaccination in Humans.Scientific reports · 2019Trial
- Data-intensive immune network modelling for One Health.Briefings in bioinformatics · 2026Review
- Innate cell markers that predict anti-HIV neutralizing antibody titers in vaccinated macaques.Cell reports. Medicine · 2022Article
- Systems Biology Approaches to Understanding the Human Immune System.Frontiers in immunology · 2020Article
- Introduction of Vaccinomics to Develop Personalized Vaccines in Light of Changes in the Usage of Hantaan Virus Vaccine (Hantavax®) in Korea.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2019Article
- SIMON, an Automated Machine Learning System, Reveals Immune Signatures of Influenza Vaccine Responses.Journal of immunology (Baltimore, Md. : 1950) · 2019Article
- Bacteriophage T4 nanoparticles for vaccine delivery against infectious diseases.Advanced drug delivery reviews · 2019Review
- Review
- Article
- Vaccinology in the third millennium: scientific and social challenges.Current opinion in virology · 2016Review
- Malaria vaccine clinical trials: what's on the horizon.Current opinion in immunology · 2015Review
- Systems vaccinology: a promise for the young and the poor.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2015Review
- New challenges in modern vaccinology.BMC immunology · 2015Review
- Designation of a novel DKK1 multiepitope DNA vaccine and inhibition of bone loss in collagen-induced arthritic mice.BioMed research international · 2015Article
- A review on computational systems biology of pathogen-host interactions.Frontiers in microbiology · 2015Review
- Systems vaccinology: probing humanity's diverse immune systems with vaccines.Proceedings of the National Academy of Sciences of the United States of America · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Numerous challenges have been identified in vaccine development, including variable efficacy as a function of population demographics and a lack of characterization and mechanistic understanding of immune correlates of protection able to guide delivery and dosing. There is tremendous opportunity in recent technological and computational advances to elucidate systems level understanding of pathogen-host interactions and correlates of immunity. A systems biology approach to vaccinology provides a new paradigm for rational vaccine design in a ‘precision medicine’ context.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.