ArticlePloS one2013
High prevalence of malaria parasitemia and anemia among hospitalized children in Rakai, Uganda.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 44 citations in OpenAlex.
- Trial
- Anaemia and blood transfusion in African children presenting to hospital with severe febrile illness.BMC medicine · 2015Trial
- Estimating Causal Effects of Malaria Infection on Anaemia Among Children Under Five Years in Uganda: Evidence From a Cross-Sectional Malaria Indicator Survey.Health science reports · 2026Article
- HLA polymorphisms shape divergent outcomes of Toxoplasma and Plasmodium infection in Eastern Indian HbE/β-thalassemia cohort.Communications biology · 2026Article
- Timeliness of blood transfusion among children admitted with severe anaemia in a tertiary hospital in Eastern Uganda: a prospective cohort study.Scientific reports · 2026Article
- Prevalence of Anemia and Its Associated Factors Among 6-59-Month-Old Children in Ayder Comprehensive Specialized Referral Hospital, Northern Ethiopia.Journal of nutrition and metabolism · 2026Article
- Clinical malaria in three ecological zones in the Volta and Oti Regions of Ghana.Malaria journal · 2025Article
- Article
- Determining the risk factors of malaria and anemia in children between 6 and 59 months using the joint generalized linear mixed model on the 2021 Nigeria Malaria Indicator Survey dataset.Frontiers in public health · 2024Article
- Malaria amongst children under five in sub-Saharan Africa: a scoping review of prevalence, risk factors and preventive interventions.European journal of medical research · 2023Article
- Sibling Species Composition and Susceptibility Status ofJournal of parasitology research · 2023Article
- Economic evaluation of postdischarge malaria chemoprevention in preschool children treated for severe anaemia in Malawi, Kenya, and Uganda: A cost-effectiveness analysis.EClinicalMedicine · 2022Article
- Individual-and community-level factors associated with anemia among children aged 6-23 months in sub-Saharan Africa: evidence from 32 sub-Saharan African countries.Archives of public health = Archives belges de sante publique · 2022Article
- Blood transfusion and mortality in children with severe anaemia in a malaria-endemic region.Paediatrics and international child health · 2021Article
- Severe Anemia Is Associated with Systemic Inflammation in Young Children Presenting to a Tertiary Hospital in Uganda.The American journal of tropical medicine and hygiene · 2020Article
- Blackwater Fever in Ugandan Children With Severe Anemia is Associated With Poor Postdischarge Outcomes: A Prospective Cohort Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020Article
- Asymptomatic SubmicroscopicThe American journal of tropical medicine and hygiene · 2020Article
- Blood transfusion requirements among children with severe malarial anemia: a cross-sectional study in a second level reference hospital in Burkina Faso.The Pan African medical journal · 2020Article
- Determinants of Anemia among women in Uganda: further analysis of the Uganda demographic and health surveys.BMC public health · 2019Article
- Article
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Authors and funding
13 authors at 7 institutions in 2 countries.
Funding
Abstract
backgroundThere is a paucity of data on malaria among hospitalized children in malaria endemic areas. We determined the prevalence, presentation and treatment outcomes of malaria and anemia among children in two hospitals in Rakai, Uganda.
methodsChildren under five years hospitalized in Kalisizo hospital or Bikira health center in Rakai district, Uganda between May 2011 and May 2012 were enrolled and followed-up until discharge, death or referral. Data were collected on social-demographic characteristics, current and past illnesses and clinical signs and symptoms. Blood smears, hemoglobin (Hgb) levels and HIV testing were performed from finger/heel prick blood. The associations between malaria infection and other factors were estimated using log-binomial regression to estimate adjusted prevalence risk ratios (aPRR) and 95% confidence intervals (CIs), controlling for clustering at health facilities.
results2471 children were enrolled. The most common medical presentations were fever (96.2%), cough (61.7%), vomiting (44.2%), diarrhea (20.8%), and seizures (16.0%). The prevalence of malaria parasitemia was 54.6%. Children with malaria were more likely to present with a history of fever (aPRR 2.23; CI 1.18-4.24) and seizures (aPRR 1.12; CI 1.09-1.16). Confirmed malaria was significantly lower among girls than boys (aPRR 0.92; CI 0.91-0.93), HIV infected children (aPRR 0.60 CI 0.52-0.71), and children with diarrhea (aPRR 0.76; CI 0.65-0.90). The overall prevalence of anemia (Hgb<10 g/dl) was 56.3% and severe anemia (Hgb<6 g/dL) was 17.8%. Among children with severe anemia 76.8% had malaria parasitemia, of whom 93.1% received blood transfusion. Malaria associated mortality was 0.6%.
conclusionThere was a high prevalence of malaria parasitemia and anemia among inpatient children under five years. Malaria prevention is a priority in this population.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.