Evidence map›Paper›PMID 24357897›Full record

ArticleSensors and actuators. B, Chemical2014

Microfluidic Valves Made From Polymerized Polyethylene Glycol Diacrylate.

Chad I Rogers, Joseph B Oxborrow, Ryan R Anderson, Long-Fang Tsai, Gregory P Nordin, Adam T Woolley

Abstract read
In one paragraph

Article in Sensors and actuators. B, Chemical, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Digital Manufacturing for Microfluidics.Annual review of biomedical engineering · 2019
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. 3D-Printed Microfluidics.Angewandte Chemie (International ed. in English) · 2016
    Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chad I RogersDepartment of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602.
Joseph B OxborrowDepartment of Electrical and Computer Engineering, Brigham Young University, Provo, Utah 84602.
Ryan R AndersonDepartment of Electrical and Computer Engineering, Brigham Young University, Provo, Utah 84602.
Long-Fang TsaiDepartment of Electrical and Computer Engineering, Brigham Young University, Provo, Utah 84602.
Gregory P NordinDepartment of Electrical and Computer Engineering, Brigham Young University, Provo, Utah 84602.
Adam T WoolleyDepartment of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602.

Funding

Phase-Changing Sacrificial Layer Microfluidics for Enhanced Protein AnalysisR01EB006124 · NIBIB · BRIGHAM YOUNG UNIVERSITY · PI WOOLLEY, ADAM THOMAS · 2006 to 2016
$3.1M
NIBIB NIH HHS R01 EB006124
6 · The paper itself

Abstract

Pneumatically actuated, non-elastomeric membrane valves fabricated from polymerized polyethylene glycol diacrylate (poly-PEGDA) have been characterized for temporal response, valve closure, and long-term durability. A ~100 ms valve opening time and a ~20 ms closure time offer valve operation as fast as 8 Hz with potential for further improvement. Comparison of circular and rectangular valve geometries indicates that the surface area for membrane interaction in the valve region is important for valve performance. After initial fabrication, the fluid pressure required to open a closed circular valve is ~50 kPa higher than the control pressure holding the valve closed. However, after ~1000 actuations to reconfigure polymer chains and increase elasticity in the membrane, the fluid pressure required to open a valve becomes the same as the control pressure holding the valve closed. After these initial conditioning actuations, poly-PEGDA valves show considerable robustness with no change in effective operation after 115,000 actuations. Such valves constructed from non-adsorptive poly-PEGDA could also find use as pumps, for application in small volume assays interfaced with biosensors or impedance detection, for example.

Indexed as

membrane valvenon-adsorptive polymernon-elastomeric polymerpneumatic actuationpoly-PEGDAvalve characterizationvalve response

Identifiers

PMID24357897
PMCPMC3864702

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.