Evidence map›Paper›PMID 24357709›Full record

ArticleBlood2013

A new view of integrin αIIbβ3 bound to membrane.

Jun Qin, Edward F Plow

Abstract readComment
In one paragraph

Article in Blood, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Jun QinCLEVELAND CLINIC.
Edward F Plow

Funding

Activation of the beta-3 integrins: Role of the KindlinsR01HL096062 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI PLOW, EDWARD FRANKLIN · 2009 to 2022
$5.6M
NHLBI NIH HHS R01 HL096062
6 · The paper itself

Abstract

In this issue of Blood, Choi et al report a 3-dimensional (3D) reconstruction model of integrin aIIbb3 in its latent state which challenges the existing paradigm and provides new insights into the mechanism of integrin activation.

Indexed as

Imaging, Three-DimensionalModels, ChemicalHumansPlatelet Glycoprotein GPIIb-IIIa ComplexPlatelet Glycoprotein GPIIb-IIIa Complex

Identifiers

PMID24357709
PMCPMC3868923

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.