Evidence map›Paper›PMID 24357510›Full record

Trial reportClinical journal of the American Society of Nephrology : CJASN2014

Sexual function, activity, and satisfaction among women receiving maintenance hemodialysis.

Maria K Mor, Mary Ann Sevick, Anne Marie Shields, Jamie A Green, Paul M Palevsky, Robert M Arnold, Michael J Fine, Steven D Weisbord

Registry-linked trialOpen access · bronzeAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Clinical journal of the American Society of Nephrology : CJASN, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00692419 (Pain, Sexual Dysfunction and Depression in Hemodialysis Patients), which is not on this map. Cited by 25 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 5 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00692419 nacompletednot on this map

Pain, Sexual Dysfunction and Depression in Hemodialysis Patients

TypeinterventionalSponsorUS Department of Veterans AffairsRan2008 to 2012Enrolled315ConditionsEnd Stage Renal Disease, Sexual Dysfunction, Physiological, Pain, DepressionArmsSymptom management nurse intervention, Feedback intervention
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 5 syntheses or guidelines pooled it, 66 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. eHealth interventions for people with chronic kidney disease.The Cochrane database of systematic reviews · 2019
    Pooled it
  5. Pooled it
  6. Trial
  7. Article
  8. Article
  9. Article
  10. Sexual bother and sexual activity before and after kidney transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Use of Sertraline in Hemodialysis Patients.Medicina (Kaunas, Lithuania) · 2021
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Maria K MorCenter for Health Equity Research and Promotion, Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, Pennsylvania;, †Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania;, ‡Department of Population Health, New York University School of Medicine, New York, New York;, §Nephrology Department, Geisinger Medical Center, Danville, Pennsylvania;, ‖Renal Section, Medicine Service Line, Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, Pennsylvania;, ¶Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, *Divisions of General Internal Medicine and, ††Palliative Care, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Mary Ann Sevick
Anne Marie Shields
Jamie A Green
Paul M Palevsky
Robert M Arnold
Michael J Fine
Steven D Weisbord
University of Pittsburgh · USVA Pittsburgh Healthcare System · USGeisinger Medical Center · USGeneral Department of Preventive Medicine · VNNew York University · US

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
NCATS NIH HHS UL1 TR000005
6 · The paper itself

Abstract

BACKGROUND AND

objectivesPast studies that demonstrated that sexual dysfunction is common among women receiving chronic hemodialysis did not distinguish sexual dysfunction/difficulty from sexual inactivity. This study sought to differentiate these in order to elucidate the prevalence of true "sexual dysfunction" in this population. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: As part of a clinical trial of symptom management strategies in patients receiving chronic hemodialysis, female sexual function was prospectively assessed monthly for 6 months and quarterly thereafter using the Female Sexual Function Index, to which questions were added differentiating sexual dysfunction/difficulty from sexual inactivity. Beginning in month 7, patients were asked three questions about sexual activity, difficulty, and satisfaction monthly.

resultsOf the women enrolled in the clinical trial,125 participants completed 1721 assessments between 2009 and 2011. Scores on 574 of 643 (89%) quarterly Female Sexual Function Index assessments were consistent with sexual dysfunction, due largely to sexual inactivity, which was reported on 525 (82%) quarterly assessments. When reported (n=1663), the most frequently described reasons for sexual inactivity were lack of interest in sex (n=715; 43%) and lack of a partner (n=647; 39%), but rarely sexual difficulty (n=36; 2%). When reported (n=1582), women were moderately to very satisfied with their sexual life on 1020 (64%) assessments and on 513 of 671 (76%) assessments in which lack of interest was cited as a reason for sexual inactivity. Women indicated an interest in learning about the causes of and treatment for sexual dysfunction on just 5% of all assessments.

conclusionsAlthough many women receiving chronic hemodialysis are sexually inactive, few describe sexual difficulty. Most, including those with a lack of interest in sex, are satisfied with their sexual life and few wish to learn about treatment options. These findings suggest that true sexual dysfunction is uncommon in this population and that treatment opportunities are rare.

Indexed as

Patient SatisfactionSexual BehaviorAgedAge FactorsFemaleHumansMiddle AgedPennsylvaniaPrevalenceProspective StudiesRenal DialysisRenal Insufficiency, ChronicRisk FactorsSex FactorsSexual Dysfunction, PhysiologicalSexual Dysfunctions, Psychological

Identifiers

PMID24357510
PMCPMC3878703
OpenAlexW2168131756

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.