ArticleInternational journal of behavioral medicine2014
Anger is associated with increased IL-6 stress reactivity in women, but only among those low in social support.
Article in International journal of behavioral medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Anger, hostility and risk of stroke: a meta-analysis of cohort studies.Journal of neurology · 2019Pooled it
- The effects of acute psychological stress on circulating and stimulated inflammatory markers: A systematic review and meta-analysis.Brain, behavior, and immunity · 2017Pooled it
- Brief Post-Surgical Stress Management Reduces Pro-Inflammatory Cytokines in Overweight and Obese Breast Cancer Patients Undergoing Primary Treatment.Frontiers in bioscience (Landmark edition) · 2022Trial
- IL-6 Response to Psychosocial Stress Predicts 12-month Changes in Cardiometabolic Biomarkers in Perimenopausal Women.The Journal of clinical endocrinology and metabolism · 2020Trial
- Roles of negative emotions and personality traits in psoriasis vulgaris: A mendelian randomization study.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024Article
- Associations between emotion reactivity to daily interpersonal stress and acute social-evaluative stress during late adolescence.Stress and health : journal of the International Society for the Investigation of Stress · 2024Article
- Biopsychosocial contexts influence adult cognitive function concurrently and longitudinally.Brain, behavior, & immunity - health · 2024Article
- Impact of Perceived Social Support on the Association Between Anger Expression and the Risk of Stroke: The Circulatory Risk in Communities Study (CIRCS).Journal of epidemiology · 2023Article
- Evidence of individual differences in the long-term social, psychological, and cognitive consequences of child maltreatment.Child and adolescent psychiatry and mental health · 2022Article
- Targeting the cannabinoid system to counteract the deleterious effects of stress in Alzheimer's disease.Frontiers in aging neuroscience · 2022Review
- Stronger functional network connectivity and social support buffer against negative affect during the COVID-19 outbreak and after the pandemic peak.Neurobiology of stress · 2021Article
- Community and Social Context: An Important Social Determinant of Cardiovascular Disease.Methodist DeBakey cardiovascular journal · 2021Review
- Urban Stress Indirectly Influences Psychological Symptoms through Its Association with Distress Tolerance and Perceived Social Support among Adults Experiencing Homelessness.International journal of environmental research and public health · 2020Article
- Gatekeeper Improves Voluntary Contractility in Patients With Fecal Incontinence.Surgical innovation · 2019Article
- The impact of psychosocial stress and stress management on immune responses in patients with cancer.Cancer · 2019Review
- Anger and Coronary Artery Disease in Women Submitted to Coronary Angiography: A 48-Month Follow-Up.Arquivos brasileiros de cardiologia · 2018Article
- The short-term stress response - Mother nature's mechanism for enhancing protection and performance under conditions of threat, challenge, and opportunity.Frontiers in neuroendocrinology · 2018Review
- Testing the stress-buffering hypothesis of social support in couples coping with early-stage dementia.PloS one · 2018Article
- Physical activity and negative affective reactivity in daily life.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2017Article
- Avoidance-related EEG asymmetry predicts circulating interleukin-6.Emotion (Washington, D.C.) · 2016Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundSocial connections moderate the effects of high negative affect on health. Affective states (anger, fear, and anxiety) predict interleukin-6 (IL-6) reactivity to acute stress; in turn, this reactivity predicts risk of cardiovascular disease progression. PURPOSE: Here, we examined whether perceived social support mitigates the relationship between negative affect and IL-6 stress reactivity.
methodForty-eight postmenopausal women completed a standardized mental lab stressor with four blood draws at baseline and 30, 50, and 90 min after the onset of the stressor and anger, anxiety, and fear were assessed 10 min after task completion. Participants self-rated levels of social support within a week prior to the stressor.
resultsOnly anger was related to IL-6 stress reactivity-those experiencing high anger after the stressor had significant increases in IL-6. IL-6 reactivity was marginally associated with perceived support, but more strikingly, perceived support mitigated anger associations with IL-6 stress reactivity.
conclusionSupportive ties can dampen the relationship of anger to pro-inflammatory reactivity to acute stress. Implications to cardiovascular disease are discussed.
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