SynthesisIrish journal of medical science2014
Dexamethasone for preventing postoperative sore throat: a meta-analysis of randomized controlled trials.
Synthesis in Irish journal of medical science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03139591 (Comparison Between Lidocaine Inhalation and Intravenous Dexamethasone to Reduce Pain After Laryngeal Mask Insertion), which is not on this map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparison Between Lidocaine Inhalation and Intravenous Dexamethasone to Reduce Pain After Laryngeal Mask Insertion
Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Nebulized pharmacological agents for preventing postoperative sore throat: A systematic review and network meta-analysis.PloS one · 2020Pooled it
- Preoperative intravenous dexamethasone prevents tracheal intubation-related sore throat in adult surgical patients: a systematic review and meta-analysis.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2019Pooled it
- Combined intraoperative paracetamol and preoperative dexamethasone reduces postoperative sore throat: a prospective randomized study.Journal of anesthesia · 2017Trial
- Comparison between intravenous lidocaine and dexamethasone in reducing postoperative sore throat after endotracheal extubation at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia; a prospective cohort study.BMC anesthesiology · 2024Article
- Observational
- Role of topical magnesium in post-operative sore throat: A systematic review and meta-analysis of randomised controlled trials.Indian journal of anaesthesia · 2019Review
- Comparison Between Lidocaine Inhalation and Intravenous Dexamethasone in Reducing Postoperative Sore Throat Frequency After Laryngeal Mask Insertion.Anesthesiology and pain medicine · 2018Article
- Effect of inhaled budesonide suspension, administered using a metered dose inhaler, on post-operative sore throat, hoarseness of voice and cough.Indian journal of anaesthesia · 2018Article
- The impact of prophylactic dexamethasone on postoperative sore throat: an updated systematic review and meta-analysis.Journal of pain research · 2018Review
- Nebulized ketamine decreases incidence and severity of post-operative sore throat.Indian journal of anaesthesia · 2015Article
- Effect of intracuff dexamethasone on incidence and severity of post operative sore -Prospective randomized study.Journal of anaesthesiology, clinical pharmacologyArticle
- Postoperative Sore Throat Prevention in Ambulatory Surgery: A Comparison between Preoperative Aspirin and Magnesium Sulfate Gargle - A Prospective, Randomized, Double-blind Study.Anesthesia, essays and researchesArticle
- Is intranasal dexamethasone effective in reducing sore throat following surgery?Tzu chi medical journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPostoperative sore throat (POST) is a common complication following tracheal intubation. The effectiveness of prophylactic dexamethasone on POST needs further elucidation.
aimsTo evaluate the effectiveness and safety of intravenous dexamethasone for the prevention of POST in patients undergoing endotracheal intubation.
methodsStudies were identified by literature searches of PubMed, Embase, and the Cochrane database. Systematic review was performed by two independent investigators.
resultsWe summarized 7 RCTs including 727 participants. Intravenous dexamethasone significantly reduced the risk of POST at 24 h [pooled risk ratio (RR) = 0.676; 95 % confidence interval (CI) 0.494-0.925; P = 0.014; heterogeneity test, I (2) = 45.8 %], as well as alleviating its severity [standardized mean difference (SMD) = -1.15; 95 % CI -1.86 to -0.45; P = 0.002; heterogeneity test, I (2) = 91.7 %]. Further sub-group analysis indicated a significant relationship between dexamethasone and reduced risk of POST when its dose was over 0.1 mg/kg. No severe adverse effects were reported.
conclusionsOur results suggest that intravenous dexamethasone reduces the risk and severity of POST from intubation at 24 h. The effective dosage of dexamethasone for preventing the risk of POST appeared to be over 0.1 mg/kg.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.