Observational studyJournal of dental research2014
Maternal oral bacterial levels predict early childhood caries development.
Observational study in Journal of dental research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00066950 (Prevention Management Model for Early Childhood Caries), which is not on this map. Cited by 42 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prevention Management Model for Early Childhood Caries
Who cites it
42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 94 citations in OpenAlex.
- Pooled it
- Prenatal Oral Health Care and Early Childhood Caries Prevention: A Systematic Review and Meta-Analysis.Caries research · 2019Pooled it
- Early Childhood Caries Intervention in Aboriginal Australian Children: A Cross-in Randomized Trial.JDR clinical and translational research · 2024Trial
- Temporal development of the oral microbiome and prediction of early childhood caries.Scientific reports · 2019Trial
- Anthropometric Measures and Early Childhood Caries: A Thai Birth Cohort Study.JDR clinical and translational research · 2026Article
- Caries risk in toddlers: assessing oral health, microbial factors, and maternal transmission.Frontiers in dental medicine · 2026Article
- Medicaid Dental Coverage and Preventive Dental Care Use Among Pregnant Adults.Maternal and child health journal · 2025Article
- A Pilot Program to Promote Maternal and Infant Oral Health Through Collaboration Between Dental and Obstetric Providers: Impact on Dental Visits During Pregnancy.Maternal and child health journal · 2025Article
- Expert consensus on the treatment of oral diseases in pregnant women and infants.International journal of oral science · 2025Review
- Antibacterial and Antibiofilm Activity of TheraBreath™ Oral Rinses: An In Vitro Study.Dentistry journal · 2025Article
- Article
- Oral health-related knowledge, practice, and utilization of dental services among pregnant women in Riyadh, Saudi Arabia.PloS one · 2025Article
- Oral health challenges during pregnancy in a semi-urban Indian population: A cross-sectional study in Valanchery, Kerala.Bioinformation · 2025Article
- Addressing Oral Health Disparities in Pregnancy: Oral Health Risk Factors and Clinical Findings at a Safety-Net Hospital in the Bronx.Women's health reports (New Rochelle, N.Y.) · 2025Article
- Effects of depression and stress on oral self-care among perinatal women in Appalachia: A longitudinal study.Community dentistry and oral epidemiology · 2024Article
- Risk of Postpartum Dental Caries: Survival Analysis of Black/African American and White Women in Appalachia.Women's health reports (New Rochelle, N.Y.) · 2024Article
- Metagenomic analysis examines oral microbiome changes and interplay with immune response following prenatal total oral rehabilitation.Journal of translational medicine · 2023Article
- Oral Health Behaviours, Knowledge, and Literacy of Expectant Mothers: A Cross-Sectional Study among Maternity Ward Patients.International journal of environmental research and public health · 2022Article
- What Do Mothers (or Caregivers) Know about Their Children's Oral Hygiene? An Update of the Current Evidence.Children (Basel, Switzerland) · 2022Review
- Microbiology-Based Instruction during Prenatal Dental Visits Improves Perinatal Oral Health Literacy.International journal of environmental research and public health · 2022Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveTo calculate the association of maternal salivary bacterial challenge (mutans streptococci [MS] and lactobacilli [LB]) from pregnancy through 24 months' postpartum with child caries incidence (≥1 cavitated or restored teeth) at 36 months. MATERIALS &
methodsDental, salivary bacterial, sociodemographic, and behavioral measures were collected at three- to six-month intervals from a birth cohort of low-income Hispanic mother-child dyads (N = 243). We calculated the relative child caries incidence, adjusted for confounding, following higher maternal challenge of MS (>4500 colony-forming units per milliliter of saliva [CFU/mL]) and LB (>50 CFU/mL) based on multivariable models.
resultsSalivary MS and LB levels were greater among mothers of caries-affected children versus caries-free children. Mothers with higher salivary MS challenge were more likely to have MS-positive children (>0 CFU/mL), but maternal LB challenge was not a statistically significant predictor of child LB-positive status. Adjusting for sociodemographics, feeding and care practices, and maternal dental status, higher maternal salivary challenge of both MS and LB over the study period predicted nearly double the child caries incidence versus lower MS and LB (cumulative incidence ratio: 1.9; 95% confidence interval: 1.1, 3.8).
conclusionMaternal salivary bacterial challenge not only is associated with oral infection among children but also predicts increased early childhood caries occurrence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.