Evidence map›Paper›PMID 24356388›Full record

ArticleJournal of perinatal medicine2014

Cervical strain determined by ultrasound elastography and its association with spontaneous preterm delivery.

Edgar Hernandez-Andrade, Roberto Romero, Steven J Korzeniewski, Hyunyoung Ahn, Alma Aurioles-Garibay, Maynor Garcia, Alyse G Schwartz, Lami Yeo, Tinnakorn Chaiworapongsa, Sonia S Hassan

Open access · bronzeAbstract read
In one paragraph

Article in Journal of perinatal medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Recommendations for strain elastography of the uterine cervix.Archives of gynecology and obstetrics · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Review
  14. Observational
  15. Article
  16. Article
  17. New techniques in evaluation of the cervix.Seminars in perinatology · 2017
    Review
  18. Cervical elastography during pregnancy: clinical perspectives.International journal of women's health · 2017
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Edgar Hernandez-Andrade
Roberto Romero
Steven J Korzeniewski
Hyunyoung Ahn
Alma Aurioles-Garibay
Maynor Garcia
Alyse G Schwartz
Lami Yeo
Tinnakorn Chaiworapongsa
Sonia S Hassan
Wayne State University · USMichigan State University · US

Funding

Prenatal Diagnosis Of Congenital AnomaliesZIAHD002401 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI ROMERO, ROBERTO · 2009 to 2025
$81.1M
Intramural NIH HHS ZIA HD002401NICHD NIH HHS HHSN275201300006C
6 · The paper itself

Abstract

objectiveTo determine if there is an association between cervical strain, evaluated using ultrasound elastography, and spontaneous preterm delivery (sPTD) <37 weeks of gestation.

methodsOne hundred and eighty nine (189) women at 16-24 weeks of gestation were evaluated. Ultrasound elastography was used to estimate cervical strain in three anatomical planes: one mid-sagittal in the same plane used for cervical length measurement, and two cross sectional images: one at the level of the internal cervical os, and the other at the level of the external cervical os. In each plane, two regions of interest (endocervix and entire cervix) were examined; a total of six regions of interest were evaluated.

resultsThe prevalence of sPTD was 11% (21/189). Strain values from each of the six cervical regions correlated weakly with cervical length (from r=-0.24, P<0.001 to r=-0.03, P=0.69). Strain measurements obtained in a cross sectional view of the internal cervical os were significantly associated with sPTD. Women with strain values ≤25th centile in the endocervical canal (0.19) and in the entire cervix (0.14) were 80% less likely to have a sPTD than women with strain values >25th centile [endocervical: odds ratio (OR) 0.2; 95% confidence interval (CI), 0.03-0.96; entire cervix: OR 0.17; 95% CI, 0.03-0.9]. Additional adjustment for gestational age, race, smoking status, parity, maternal age, pre-pregnancy body mass index, and previous preterm delivery did not appreciably alter the magnitude or statistical significance of these associations. Strain values obtained from the external cervical os and from the sagittal view were not associated with sPTD.

conclusionLow strain values in the internal cervical os were associated with a significantly lower risk of spontaneous preterm delivery <37 weeks of gestation.

Indexed as

AdolescentAdultCervical Length MeasurementCervix UteriCross-Sectional StudiesElasticity Imaging TechniquesFemaleHumansPregnancyPremature BirthStress, MechanicalYoung Adult

Identifiers

PMID24356388
PMCPMC4183449
OpenAlexW2010142682

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.