Evidence map›Paper›PMID 24356235›Full record

ArticleInvestigative ophthalmology & visual science2013

Understanding RPE lipofuscin.

Janet R Sparrow, John E Dowling, Dean Bok

Abstract readLetterComment
In one paragraph

Article in Investigative ophthalmology & visual science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Mitophagy: An Emerging Target in Ocular Pathology.Investigative ophthalmology & visual science · 2021
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Lipofuscin-dependent stimulation of microglial cells.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2019
    Article
  10. Article
  11. Robust lysosomal calcium signaling through channel TRPML1 is impaired by lysosomal lipid accumulation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2018
    Article
  12. Review
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Janet R SparrowDepartments of Ophthalmology and Pathology and Cell Biology, Columbia University, New York, New York;
John E Dowling
Dean Bok

Funding

IMPACT OF LIPOFUSCIN IN RETINAL PIGMENT EPITHELIAL CELLSR01EY012951 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SPARROW, JANET RUTHE · 2000 to 2024
$8.9M
NEI NIH HHS R01 EY012951
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HumansRetinal DegenerationRetinal Pigment EpitheliumRetinoidsRetinoids

Identifiers

PMID24356235
PMCPMC4830350

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.