ArticleJournal of perinatology : official journal of the California Perinatal Association2014
Coagulase-negative staphylococcus sepsis in preterm infants and long-term neurodevelopmental outcome.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03730883 (The Effect of Early Versus Standard Central Line Removal on Growth of Very Low Birth Weight Premature Infants), which is not on this map. Cited by 29 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Early Versus Standard Central Line Removal on Growth of Very Low Birth Weight Premature Infants: A Non-inferiority, Randomized Controlled Trial
Who cites it
29 citing papers in PubMed, 5 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Biological markers of hearing loss in neonates admitted to the neonatal intensive care unit: a systematic review and meta-analysis.Frontiers in neuroscience · 2026Pooled it
- Impact of neonatal sepsis on neurocognitive outcomes: a systematic review and meta-analysis.BMC pediatrics · 2024Pooled it
- Global prevalence of long-term neurodevelopmental impairment following extremely preterm birth: a systematic literature review.The Journal of international medical research · 2021Pooled it
- Association of Histological and Clinical Chorioamnionitis With Neonatal Sepsis Among Preterm Infants: A Systematic Review, Meta-Analysis, and Meta-Regression.Frontiers in immunology · 2020Pooled it
- Antibiotics at the time of removal of central venous catheter to reduce morbidity and mortality in newborn infants.The Cochrane database of systematic reviews · 2018Pooled it
- Trial
- Optimised versus standard dosing of vancomycin in infants with Gram-positive sepsis (NeoVanc): a multicentre, randomised, open-label, phase 2b, non-inferiority trial.The Lancet. Child & adolescent health · 2022Trial
- Epidemiology and Outcomes of Neonatal Sepsis: Experience from a Tertiary Australian NICU.Neonatology · 2024Article
- The Role of Coagulase-Negative Staphylococci Biofilms on Late-Onset Sepsis: Current Challenges and Emerging Diagnostics and Therapies.Antibiotics (Basel, Switzerland) · 2023Review
- Isolation and Identification ofVeterinary sciences · 2022Article
- Look Who's Talking: Host and Pathogen Drivers ofInternational journal of molecular sciences · 2022Review
- Altered Gut Microbiome and Fecal Immune Phenotype in Early Preterm Infants With Leaky Gut.Frontiers in immunology · 2022Article
- Can EEG accurately predict 2-year neurodevelopmental outcome for preterm infants?Archives of disease in childhood. Fetal and neonatal edition · 2021Observational
- Association of Infection in Neonates and Long-Term Neurodevelopmental Outcome.Clinics in perinatology · 2021Review
- Article
- Commensal Staphylococci Including Methicillin-Resistant Staphylococcus aureus from Dogs and Cats in Remote New South Wales, Australia.Microbial ecology · 2020Article
- Short- and Long-Term Neurodevelopmental Outcomes of Very Preterm Infants with Neonatal Sepsis: A Systematic Review and Meta-Analysis.Children (Basel, Switzerland) · 2019Review
- Article
- Neurodevelopmental outcome at 2 years of age in preterm infants with late-onset sepsis.European journal of pediatrics · 2019Article
- Rational Use of Antibiotics in Neonates: Still in Search of Tailored Tools.Healthcare (Basel, Switzerland) · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe objective of this study was to examine the impact of Coagulase-negative staphylococcus (CoNS) sepsis in preterm infants on the neurodevelopmental outcomes at 30 to 42 months corrected age (CA). STUDY
designThis is a retrospective cohort study. All preterm infants born at <29 weeks gestational age between 1995 and 2008 and had a neurodevelopmetnal assessment at 30 to 42 months CA were eligible. The neurodevelopmetnal outcomes of infants exposed to CoNS sepsis were compared with infants unexposed to any type of neonatal sepsis.
resultA total of 105 eligible infants who were exposed to CoNS sepsis were compared with 227 infants with no neonatal sepsis. In univariate analysis, infants with CoNS sepsis were more likely to have total major disability (odds ratio (OR)=1.9; 95% CI: 1.07 to 3.38) and cognitive delay (OR=2.53; 1.26 to 5.14).There was no significant difference in the incidence of cerebral palsy, blindness and deafness between the two groups. After correcting for potential confounders, CoNS sepsis was associated with increased risk of cognitive delay (adjusted odds ratio (aOR)= 2.23; 95% CI 1.01 to 4.9), but not with the total major disability (aOR=1.14; 95% CI: 0.55 to 2.34).
conclusionOur study suggests that CoNS sepsis in preterm infants might be associated with increased risk for cognitive delay at 36 months CA.
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Registered trials
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