Evidence map›Paper›PMID 24355745›Full record

Observational studyInternational journal of epidemiology2014

Child mortality patterns in rural Tanzania: an observational study on the impact of malaria control interventions.

Sandra Alba, Rose Nathan, Alexander Schulze, Hassan Mshinda, Christian Lengeler

Abstract readObservational Study
In one paragraph

Observational study in International journal of epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Intermittent preventive antimalarial treatment for children with anaemia.The Cochrane database of systematic reviews · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sandra AlbaRoyal Tropical Institute (KIT), KIT Biomedical Research, Amsterdam, The Netherlands, Ifakara Health Institute, Dar es Salaam, Tanzania, Novartis Foundation for Sustainable Development, Basel, Switzerland, Tanzania Commission for Science and Technology, Dar es Salaam, Tanzania, Swiss Tropical and Public Health Institute, Department of Epidemiology and Public Health, Switzerland and Faculty of Science, University of Basel, Basel, Switzerland.
Rose Nathan
Alexander Schulze
Hassan Mshinda
Christian Lengeler

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBetween 1997 and 2009, a number of key malaria control interventions were implemented in the Kilombero and Ulanga Districts in south central Tanzania to increase insecticide-treated nets (ITN) coverage and improve access to effective malaria treatment. In this study we estimated the contribution of these interventions to observed decreases in child mortality.

methodsThe local Health and Demographic Surveillance Site (HDSS) provided monthly estimates of child mortality rates (age 1 to 5 years) expressed as cases per 1000 person-years (c/1000py) between 1997 and 2009. We conducted a time series analysis of child mortality rates and explored the contribution of rainfall and household food security. We used Poisson regression with linear and segmented effects to explore the impact of malaria control interventions on mortality.

resultsChild mortality rates decreased by 42.5% from 14.6 c/1000py in 1997 to 8.4 c/1000py in 2009. Analyses revealed the complexity of child mortality patterns and a strong association with rainfall and food security. All malaria control interventions were associated with decreases in child mortality, accounting for the effect of rainfall and food security.

conclusionsReaching the fourth Millenium Development Goal will require the contribution of many health interventions, as well as more general improvements in socio-environmental and nutritional conditions. Distinguishing between the effects of these multiple factors is difficult and represents a major challenge in assessing the effect of routine interventions. However, this study suggests that credible estimates can be obtained when high-quality data on the most important factors are available over a sufficiently long time period.

Indexed as

Child MortalityAntimalarialsChildFemaleFood SupplyHealth Services AccessibilityHumansInsecticide-Treated BednetsMalariaMaleMosquito ControlNutritional StatusRural PopulationSeasonsSocioeconomic FactorsTanzaniaAntimalarialschild mortalityfood securityMalariamalaria control interventionsmortality impactrainfall

Identifiers

PMID24355745
PMCPMC3937976

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.