Evidence map›Paper›PMID 24355537›Full record

SynthesisBMJ (Clinical research ed.)2013

Dietary fibre intake and risk of cardiovascular disease: systematic review and meta-analysis.

Diane E Threapleton, Darren C Greenwood, Charlotte E L Evans, Christine L Cleghorn, Camilla Nykjaer, Charlotte Woodhead, Janet E Cade, Christopher P Gale, Victoria J Burley

Registry-linked trialOpen access · hybridAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMJ (Clinical research ed.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04887584 (Identifying the Role of Pulses in a Healthful Diet), which is not on this map. Cited by 309 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
309citing papers in PubMed, 16 pooled it
29.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04887584 nacompletednot on this mapstarted 2022, after this paper: background citation

Identifying the Role of Pulses in a Healthful Diet: Metabolomic Signatures of Dietary Pulses and Their Benefits on Cardiometabolic Risk Factors

TypeinterventionalSponsorUSDA, Western Human Nutrition Research CenterRan2022 to 2023Enrolled20ConditionsBody WeightArmsControl diet, Low Pulse diet, High Pulse diet
3 · Its place in the literature

Who cites it

309 citing papers in PubMed, 16 syntheses or guidelines pooled it, 740 citations in OpenAlex.

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249 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Diane E ThreapletonNutritional Epidemiology Group, School of Food Science and Nutrition, University of Leeds, Leeds LS2 9JT, UK.
Darren C Greenwood
Charlotte E L Evans
Christine L Cleghorn
Camilla Nykjaer
Charlotte Woodhead
Janet E Cade
Christopher P Gale
Victoria J Burley
University of Leeds · GB

Funding

Department of Health
6 · The paper itself

Abstract

objectiveTo investigate dietary fibre intake and any potential dose-response association with coronary heart disease and cardiovascular disease.

designSystematic review of available literature and dose-response meta-analysis of cohort studies using random effects models. DATA SOURCES: The Cochrane Library, Medline, Medline in-process, Embase, CAB Abstracts, ISI Web of Science, BIOSIS, and hand searching. ELIGIBILITY CRITERIA FOR STUDIES: Prospective studies reporting associations between fibre intake and coronary heart disease or cardiovascular disease, with a minimum follow-up of three years and published in English between 1 January 1990 and 6 August 2013.

results22 cohort study publications met inclusion criteria and reported total dietary fibre intake, fibre subtypes, or fibre from food sources and primary events of cardiovascular disease or coronary heart disease. Total dietary fibre intake was inversely associated with risk of cardiovascular disease (risk ratio 0.91 per 7 g/day (95% confidence intervals 0.88 to 0.94)) and coronary heart disease (0.91 (0.87 to 0.94)). There was evidence of some heterogeneity between pooled studies for cardiovascular disease (I(2)=45% (0% to 74%)) and coronary heart disease (I(2)=33% (0% to 66%)). Insoluble fibre and fibre from cereal and vegetable sources were inversely associated with risk of coronary heart disease and cardiovascular disease. Fruit fibre intake was inversely associated with risk of cardiovascular disease.

conclusionsGreater dietary fibre intake is associated with a lower risk of both cardiovascular disease and coronary heart disease. Findings are aligned with general recommendations to increase fibre intake. The differing strengths of association by fibre type or source highlight the need for a better understanding of the mode of action of fibre components.

Indexed as

Cardiovascular DiseasesCoronary DiseaseDietary FiberEdible GrainEvidence-Based MedicineHumansPractice Guidelines as TopicRisk AssessmentRisk FactorsVegetablesDietary Fiber

Identifiers

PMID24355537
PMCPMC3898422
OpenAlexW2122031089

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.