Evidence map›Paper›PMID 24354783›Full record

ArticleJournal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]

Critical appraisal: Cross-linkers and the dentin matrix.

David Farias, Patricia A Miguez, Edward J Swift

Abstract readComment
PubMed Publisher
In one paragraph

Article in Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Molecular interactions of tannic acid and matrix metalloproteinases 2 and 9.Computational and structural biotechnology journal · 2023
    Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

David FariasDepartment of Dentistry, Federal University of Santa Catarina, Brazil.
Patricia A Miguez
Edward J Swift

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The formation of a hybrid layer is essential for successful dentin bonding and is achieved by adhesive penetration between exposed collagen fibrils in the demineralized dentin. Incomplete infiltration of the adhesive within the collagen network results in exposed fibrils, which may suffer enzymatic degradation over time. Methods to increase collagen resistance to proteinases (enzymes that degrade proteins) have been studied. One particular approach is to use collagen cross-linking agents that modify collagen through addition of specific or random amino acid linkage between and within its molecules. This Critical Appraisal provides information on the effects of various cross-linkers on dentin collagen stability, dentin properties, and resin-dentin bond strengths, and calls for critical thinking on the potential effects of this therapeutic approach.

Indexed as

Ultraviolet RaysVitisCollagenCross-Linking ReagentsDental BondingDentinDentin-Bonding AgentsElectrophoresis, Polyacrylamide GelGlutaralGrape Seed ExtractHumansProanthocyanidinsResin CementsRiboflavinTanninsCollagenCross-Linking ReagentsDentin-Bonding AgentsGlutaralGrape Seed ExtractProanthocyanidinsResin CementsRiboflavinTannins

Identifiers

PMID24354783

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.