ArticleChild and adolescent psychiatry and mental health2013
The Nordic long-term OCD treatment study (NordLOTS): rationale, design, and methods.
Article in Child and adolescent psychiatry and mental health, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 75 citations in OpenAlex.
- Family-based cognitive behavioral therapy versus family-based psychoeducation and relaxation training for obsessive-compulsive disorder in children and adolescents: a randomized clinical trial (TECTO).European child & adolescent psychiatry · 2025Trial
- Trial
- Sertraline Treatment of Nonresponders to Extended Cognitive-Behavior Therapy in Pediatric Obsessive-Compulsive Disorder.Journal of child and adolescent psychopharmacology · 2015Trial
- Tics Moderate Sertraline, but Not Cognitive-Behavior Therapy Response in Pediatric Obsessive-Compulsive Disorder Patients Who Do Not Respond to Cognitive-Behavior Therapy.Journal of child and adolescent psychopharmacology · 2015Trial
- Continued cognitive-behavior therapy versus sertraline for children and adolescents with obsessive-compulsive disorder that were non-responders to cognitive-behavior therapy: a randomized controlled trial.European child & adolescent psychiatry · 2015Trial
- Three-Year Follow-Up of children and adolescents with OCD Who Did Not Respond to Initial Cognitive-Behavioral Therapy (CBT): Outcomes of Continued CBT vs. Sertraline.European child & adolescent psychiatry · 2026Article
- Online CBT Versus Standard CBT for Pediatric Obsessive-Compulsive Disorder.Child psychiatry and human development · 2026Article
- Psychotic vulnerability in pediatric obsessive-compulsive disorder: associations with clinical features and treatment outcome in two clinical samples.European child & adolescent psychiatry · 2025Article
- Family Accommodation in Pediatric Obsessive-Compulsive Disorder: Investigating Prevalence and Clinical Correlates in the NordLOTS Study.Child psychiatry and human development · 2025Article
- Adverse events in cognitive behavioral therapy and relaxation training for children and adolescents with obsessive-compulsive disorder: A mixed methods study and analysis plan for the TECTO trial.Contemporary clinical trials communications · 2023Article
- Do Autistic Traits Predict Outcome of Cognitive Behavioral Therapy in Pediatric Obsessive-Compulsive Disorder?Research on child and adolescent psychopathology · 2023Article
- Quality of life in pediatric patients with obsessive-compulsive disorder during and 3 years after stepped-care treatment.European child & adolescent psychiatry · 2022Article
- Scoping review of stepped care interventions for mental health and substance use service delivery to youth and young adults.Early intervention in psychiatry · 2022Article
- Article
- Neurochemical properties measured byJournal of neural transmission (Vienna, Austria : 1996) · 2021Article
- Symptom Trajectories of Early Responders and Remitters among Youth with OCD.Journal of obsessive-compulsive and related disorders · 2020Article
- Avoidance, Insight, Impairment Recognition Concordance, and Cognitive-Behavioral Therapy Outcomes in Pediatric Obsessive-Compulsive Disorder.Journal of the American Academy of Child and Adolescent Psychiatry · 2020Article
- Towards a Clinically Valid Mechanistic Assessment of Exposure and Response Prevention: Preliminary Utility of an Exposure Learning Tool for Children with OCD.Journal of obsessive-compulsive and related disorders · 2020Article
- Hoarding in children and adolescents with obsessive-compulsive disorder: prevalence, clinical correlates, and cognitive behavioral therapy outcome.European child & adolescent psychiatry · 2019Article
- The Validity of the Screen for Child Anxiety Related Emotional Disorders Revised (SCARED-R) Scale and Sub-Scales in Swedish Youth.Child psychiatry and human development · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis paper describes and discusses the methodology of the Nordic long-term OCD-treatment study (NordLOTS). The purpose of this effectiveness study was to study treatment outcome of CBT, to identify CBT non- or partial responders and to investigate whether an increased number of CBT-sessions or sertraline treatment gives the best outcome; to identify treatment refractory patients and to investigate the outcome of aripiprazole augmentation; to study the outcome over a three year period for each responder including the risk of relapse, and finally to study predictors, moderators and mediators of treatment response.
methodsStep 1 was an open and uncontrolled clinical trial with CBT, step 2 was a controlled, randomised non-blinded study of CBT non-responders from step 1. Patients were randomized to receive either sertraline plus CBT-support or continued and modified CBT. In step 3 patients who did not respond to either CBT or sertraline were treated with aripiprazole augmentation to sertraline.
conclusionsThis multicenter trial covering three Scandinavian countries is going to be the largest CBT-study for paediatric OCD to date. It is not funded by industry and tries in the short and long-term to answer the question whether further CBT or SSRI is better in CBT non-responders.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.