Evidence map›Paper›PMID 24354653›Full record

GuidelineJournal of the European Academy of Dermatology and Venereology : JEADV2014

Guidelines on the use of extracorporeal photopheresis.

R Knobler, G Berlin, P Calzavara-Pinton, H Greinix, P Jaksch, L Laroche, J Ludvigsson, P Quaglino, W Reinisch, J Scarisbrick and 30 more

Registry-linked trialAbstract readPractice Guideline
In one paragraph

Guideline in Journal of the European Academy of Dermatology and Venereology : JEADV, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04752397 (The Influence of Extracorporeal Photopheresis on Skin Sclerosis - an Exploratory Clinical Study), which is not on this map. Cited by 69 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04752397 completednot on this mapstarted 2021, after this paper: background citation

The Influence of Extracorporeal Photopheresis on Skin Sclerosis - an Exploratory Clinical Study

TypeobservationalSponsorCharite University, Berlin, GermanyRan2021 to 2021Enrolled6ConditionsScleroderma, Systemic, Graft Vs Host Disease, Eosinophilic Fasciitis, Morphea
3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Extracorporeal photopheresis-New insights into an old procedure.Transfusion medicine (Oxford, England) · 2026
    Trial
  3. Trial
  4. Review
  5. Article
  6. Review
  7. Review
  8. Current Usage of Extracorporeal Photopheresis in Solid Organ Transplantations in Europe: A Narrative Review.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Extracorporeal Photopheresis in Dermatological Diseases.International journal of molecular sciences · 2024
    Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. What Is New in Cutaneous T Cell Lymphoma?Current oncology reports · 2023
    Review
  19. Article
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

40 authors.

R KnoblerDepartment of Dermatology, Medical University of Vienna, Vienna, Austria.
G Berlin
P Calzavara-Pinton
H Greinix
P Jaksch
L Laroche
J Ludvigsson
P Quaglino
W Reinisch
J Scarisbrick
T Schwarz
P Wolf
P Arenberger
C Assaf
M Bagot
M Barr
A Bohbot
L Bruckner-Tuderman
B Dreno
A Enk
L French
R Gniadecki
H Gollnick
M Hertl
C Jantschitsch
A Jung
U Just
C-D Klemke
U Lippert
T Luger
E Papadavid
H Pehamberger
A Ranki
R Stadler
W Sterry
I H Wolf
M Worm
J Zic
C C Zouboulis
U Hillen

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAfter the first investigational study on the use of extracorporeal photopheresis for the treatment of cutaneous T-cell lymphoma was published in 1983 with its subsequent recognition by the FDA for its refractory forms, the technology has shown significant promise in the treatment of other severe and refractory conditions in a multi-disciplinary setting. Among the major studied conditions are graft versus host disease after allogeneic bone marrow transplantation, systemic sclerosis, solid organ transplant rejection and inflammatory bowel disease. MATERIALS AND

methodsIn order to provide recognized expert practical guidelines for the use of this technology for all indications the European Dermatology Forum (EDF) proceeded to address these questions in the hands of the recognized experts within and outside the field of dermatology. This was done using the recognized and approved guidelines of EDF for this task. RESULTS AND

conclusionThese guidelines provide at present the most comprehensive available expert recommendations for the use of extracorporeal photopheresis based on the available published literature and expert consensus opinion.

Indexed as

Autoimmune DiseasesGraft RejectionGraft vs Host DiseaseHumansInflammatory Bowel DiseasesLymphoma, T-Cell, CutaneousPhotopheresisPhotosensitizing AgentsScleroderma, SystemicSkin NeoplasmsTreatment OutcomePhotosensitizing Agents

Identifiers

PMID24354653
PMCPMC4291097

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.