ArticleSchizophrenia bulletin2014
Prevalence and clinical significance of DSM-5-attenuated psychosis syndrome in adolescents and young adults in the general population: the Bern Epidemiological At-Risk (BEAR) study.
Article in Schizophrenia bulletin, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 88 citations in OpenAlex.
- Establishing a clinical service to prevent psychosis: What, how and when? Systematic review.Translational psychiatry · 2021Pooled it
- The Dark Side of the Moon: Meta-analytical Impact of Recruitment Strategies on Risk Enrichment in the Clinical High Risk State for Psychosis.Schizophrenia bulletin · 2016Pooled it
- Mapping Schizotypy and Subthreshold Psychotic Experiences in a Resilience-Risk Network: Insights from a Population-Based Study.Schizophrenia bulletin open · 2026Article
- Feasibility of a Stepped-Care Intervention for Those at Clinical High Risk for Psychosis in the United States.Early intervention in psychiatry · 2026Article
- Clinical and neurocognitive profiles of a combined clinical high risk for psychosis and clinical control sample: latent class analysis.BJPsych open · 2024Article
- Development of the PSYCHS: Positive SYmptoms and Diagnostic Criteria for the CAARMS Harmonized with the SIPS.Early intervention in psychiatry · 2024Article
- Development of the PSYCHS: Positive SYmptoms and Diagnostic Criteria for the CAARMS Harmonized with the SIPS.medRxiv : the preprint server for health sciences · 2023Article
- Influence of mental health literacy on help-seeking behaviour for mental health problems in the Swiss young adult community: a cohort and longitudinal case-control study.European archives of psychiatry and clinical neuroscience · 2023Article
- The Important Role of Stereotypes in the relation between Mental Health Literacy and Stigmatization of Depression and Psychosis in the Community.Community mental health journal · 2022Article
- Perceived Family Functioning Profile in Adolescents at Clinical High Risk for Psychosis: Rigidity as a Possible Preventive Target.Frontiers in psychiatry · 2022Article
- Prevalence of Individuals at Clinical High-Risk of Psychosis in the General Population and Clinical Samples: Systematic Review and Meta-Analysis.Brain sciences · 2021Review
- Prognostic Accuracy of DSM-5 Attenuated Psychosis Syndrome in Adolescents: Prospective Real-World 5-Year Cohort Study.Schizophrenia bulletin · 2021Article
- Risk and protective factors for mental disorders beyond genetics: an evidence-based atlas.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2021Article
- Predictors of help-seeking behaviour in people with mental health problems: a 3-year prospective community study.BMC psychiatry · 2021Article
- Preventive psychiatry: a blueprint for improving the mental health of young people.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2021Article
- Screening of the college students at clinical high risk for psychosis in China: a multicenter epidemiological study.BMC psychiatry · 2021Article
- Effects of age and sex on clinical high-risk for psychosis in the community.World journal of psychiatry · 2020Article
- Age effects on basic symptoms in the community: A route to gain new insight into the neurodevelopment of psychosis?European archives of psychiatry and clinical neuroscience · 2020Article
- Basic Symptoms Are Associated With Age in Patients With a Clinical High-Risk State for Psychosis: Results From the PRONIA Study.Frontiers in psychiatry · 2020Article
- Does hallucination perceptual modality impact psychosis risk?Acta psychiatrica Scandinavica · 2019Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveSection III of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) lists attenuated psychosis syndrome as a condition for further study. One important question is its prevalence and clinical significance in the general population.
methodAnalyses involved 1229 participants (age 16-40 years) from the general population of Canton Bern, Switzerland, enrolled from June 2011 to July 2012. "Symptom," "onset/worsening," "frequency," and "distress/disability" criteria of attenuated psychosis syndrome were assessed using the structured interview for psychosis-risk syndromes. Furthermore, help-seeking, psychosocial functioning, and current nonpsychotic axis I disorders were surveyed. Well-trained psychologists performed assessments using the computer-assisted telephone interviewing technique.
resultsThe symptom criterion was met by 12.9% of participants, onset/worsening by 1.1%, frequency by 3.8%, and distress/disability by 7.0%. Symptom, frequency, and distress/disability were met by 3.2%. Excluding trait-like attenuated psychotic symptoms (APS) decreased the prevalence to 2.6%, while adding onset/worsening reduced it to 0.3%. APS were associated with functional impairments, current mental disorders, and help-seeking although they were not a reason for help-seeking. These associations were weaker for attenuated psychosis syndrome.
conclusionsAt the population level, only 0.3% met current attenuated psychosis syndrome criteria. Particularly, the onset/worsening criterion, originally included to increase the likelihood of progression to psychosis, lowered its prevalence. Because progression is not required for a self-contained syndrome, a revision of the restrictive onset criterion is proposed to avoid the exclusion of 2.3% of persons who experience and are distressed by APS from mental health care. Secondary analyses suggest that a revised syndrome would also possess higher clinical significance than the current syndrome.
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