ArticleEcotoxicology (London, England)2014
Toxicological effects of the sunscreen UV filter, benzophenone-2, on planulae and in vitro cells of the coral, Stylophora pistillata.
Article in Ecotoxicology (London, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 109 citations in OpenAlex.
- What are the toxicity thresholds of chemical pollutants for tropical reef-building corals? A systematic review.Environmental evidence · 2023Pooled it
- Sublethal effects of contaminants on marine habitat-forming species: a review and meta-analysis.Biological reviews of the Cambridge Philosophical Society · 2020Pooled it
- Article
- Organic Sunscreens-Biological Activity from an Enzymatic Perspective.Molecules (Basel, Switzerland) · 2026Article
- Article
- Complete Characterization of Degradation Byproducts of Bemotrizinol and Degradation Pathway Associated with Sodium Hypochlorite Treatment.Molecules (Basel, Switzerland) · 2025Article
- Article
- Single-polyp metabolomics for coral health assessment.Scientific reports · 2024Article
- Reality check: What can we expect from an ecological risk assessment of UV filters on coral reefs?Integrated environmental assessment and management · 2024Article
- Towards Precision Ecotoxicology: Leveraging Evolutionary Conservation of Pharmaceutical and Personal Care Product Targets to Understand Adverse Outcomes Across Species and Life Stages.Environmental toxicology and chemistry · 2024Review
- Seaweeds and Corals from the Brazilian Coast: Review on Biotechnological Potential and Environmental Aspects.Molecules (Basel, Switzerland) · 2023Review
- On the Fate of Butyl Methoxydibenzoylmethane (Avobenzone) in Coral Tissue and Its Effect on Coral Metabolome.Metabolites · 2023Article
- Article
- Development of a Survey of Sunscreen Use and Attitudes among Adults in Two Coastal States, 2019.International journal of environmental research and public health · 2022Article
- Unravelling the Photoprotection Properties of Garden Cress Sprout Extract.Molecules (Basel, Switzerland) · 2021Article
- Coral Ecotoxicological Data Evaluation for the Environmental Safety Assessment of Ultraviolet Filters.Environmental toxicology and chemistry · 2021Article
- UV-filter pollution: current concerns and future prospects.Environmental monitoring and assessment · 2021Review
- Exposure to four chemical UV filters through contaminated sediment: impact on survival, hatching success, cardiac frequency, and aerobic metabolic scope in embryo-larval stage of zebrafish.Environmental science and pollution research international · 2021Article
- Applying model approaches in non-model systems: A review and case study on coral cell culture.PloS one · 2021Review
- Unravelling the Photoprotective Mechanisms of Nature-Inspired Ultraviolet Filters Using Ultrafast Spectroscopy.Molecules (Basel, Switzerland) · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Benzophenone-2 (BP-2) is an additive to personal-care products and commercial solutions that protects against the damaging effects of ultraviolet light. BP-2 is an "emerging contaminant of concern" that is often released as a pollutant through municipal and boat/ship wastewater discharges and landfill leachates, as well as through residential septic fields and unmanaged cesspits. Although BP-2 may be a contaminant on coral reefs, its environmental toxicity to reefs is unknown. This poses a potential management issue, since BP-2 is a known endocrine disruptor as well as a weak genotoxicant. We examined the effects of BP-2 on the larval form (planula) of the coral, Stylophora pistillata, as well as its toxicity to in vitro coral cells. BP-2 is a photo-toxicant; adverse effects are exacerbated in the light versus in darkness. Whether in darkness or light, BP-2 induced coral planulae to transform from a motile planktonic state to a deformed, sessile condition. Planulae exhibited an increasing rate of coral bleaching in response to increasing concentrations of BP-2. BP-2 is a genotoxicant to corals, exhibiting a strong positive relationship between DNA-AP lesions and increasing BP-2 concentrations. BP-2 exposure in the light induced extensive necrosis in both the epidermis and gastro dermis. In contrast, BP-2 exposure in darkness induced autophagy and autophagic cell death.The LC50 of BP-2 in the light for an 8 and 24 hour exposure was 120 parts per million (ppm) and 165 parts per billion (ppb), respectively. The LC50s for BP-2 in darkness for the same time points were 144 parts per million and 548 parts per billion [corrected].
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.