ReviewJournal of the Royal Society, Interface2014
Current concepts: tissue engineering and regenerative medicine applications in the ankle joint.
Review in Journal of the Royal Society, Interface, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Current Utilization of Gel-Based Scaffolds and Templates in Foot and Ankle Surgery-A Review.Gels (Basel, Switzerland) · 2025Review
- All Arthroscopic Osteochondral Autograft Transplantation for Medial Talar Dome Lesions Talus With Burring of the Anterior Lip of the Distal Tibia.Arthroscopy techniques · 2024Article
- Recent Applications of Electrospun Nanofibrous Scaffold in Tissue Engineering.Applied bionics and biomechanics · 2022Review
- Poly(lactic-Bioactive materials · 2021Review
- A Full Set of In Vitro Assays in Chitosan/Tween 80 Microspheres Loaded with Magnetite Nanoparticles.Polymers · 2021Article
- Article
- Biomaterials for the Treatment of Tendon Injury.Tissue engineering and regenerative medicine · 2019Review
- Ex vivo MRI cell tracking of autologous mesenchymal stromal cells in an ovine osteochondral defect model.Stem cell research & therapy · 2019Article
- The Crosstalk Between Osteodifferentiating Stem Cells and Endothelial Cells Promotes Angiogenesis and Bone Formation.Frontiers in physiology · 2019Article
- Osteogenic Differentiation Modulates the Cytokine, Chemokine, and Growth Factor Profile of ASCs and SHED.International journal of molecular sciences · 2018Article
- A Clinical, Biological, and Biomaterials Perspective into Tendon Injuries and Regeneration.Tissue engineering. Part B, Reviews · 2017Article
- Artificial Bone via Bone Tissue Engineering: Current Scenario and Challenges.Tissue engineering and regenerative medicine · 2017Review
- Osteogenesis evaluation of duck's feet-derived collagen/hydroxyapatite sponges immersed in dexamethasone.Biomaterials research · 2017Article
- Article
- The importance of stem cell engineering in head and neck oncology.Biotechnology letters · 2016Review
- Long-term results of microfracture in the treatment of talus osteochondral lesions.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2016Article
- [Three-dimensional parallel collagen scaffold promotes tendon extracellular matrix formation].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2016Article
- IGF-I induces adipose derived mesenchymal cell chondrogenic differentiation in vitro and enhances chondrogenesis in vivo.In vitro cellular & developmental biology. Animal · 2016Article
- Osteoinduction and proliferation of bone-marrow stromal cells in three-dimensional poly (ε-caprolactone)/ hydroxyapatite/collagen scaffolds.Journal of translational medicine · 2015Article
- Multipotent adult progenitor cells on an allograft scaffold facilitate the bone repair process.Journal of tissue engineeringArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tissue engineering and regenerative medicine (TERM) has caused a revolution in present and future trends of medicine and surgery. In different tissues, advanced TERM approaches bring new therapeutic possibilities in general population as well as in young patients and high-level athletes, improving restoration of biological functions and rehabilitation. The mainstream components required to obtain a functional regeneration of tissues may include biodegradable scaffolds, drugs or growth factors and different cell types (either autologous or heterologous) that can be cultured in bioreactor systems (in vitro) prior to implantation into the patient. Particularly in the ankle, which is subject to many different injuries (e.g. acute, chronic, traumatic and degenerative), there is still no definitive and feasible answer to 'conventional' methods. This review aims to provide current concepts of TERM applications to ankle injuries under preclinical and/or clinical research applied to skin, tendon, bone and cartilage problems. A particular attention has been given to biomaterial design and scaffold processing with potential use in osteochondral ankle lesions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.