ArticleThe Journal of investigative dermatology2014
The impact of MITF on melanoma development: news from bench and bedside.
Article in The Journal of investigative dermatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 12 citations in OpenAlex.
- Genetic Variants and Somatic Alterations Associated with MITF-E318K Germline Mutation in Melanoma Patients.Genes · 2021Article
- Sustained androgen receptor signaling is a determinant of melanoma cell growth potential and tumorigenesis.The Journal of experimental medicine · 2021Article
- Depletion of p42.3 gene inhibits proliferation and invasion in melanoma cells.Journal of cancer research and clinical oncology · 2017Article
- Cuprous oxide nanoparticle-inhibited melanoma progress by targeting melanoma stem cells.International journal of nanomedicine · 2017Article
- Hereditary melanoma: Update on syndromes and management: Emerging melanoma cancer complexes and genetic counseling.Journal of the American Academy of Dermatology · 2016Review
- Parthenolide induces MITF-M downregulation and senescence in patient-derived MITF-M(high) melanoma cell populations.Oncotarget · 2016Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
In the current issue, two articles highlight the impact of melanocyte transcription factor (MITF) on melanoma development. In the first, Lister et al. reveal in vivo proof of MITF directly regulating tumor development in BRAF(V600E) melanomas. In the second, Sturm et al. present a clinical trial that emphasizes the importance of the recently discovered E318K MITF germline mutation in patients with multiple primary melanomas.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.