ArticlePlant physiology2014
MicroRNA156: a potential graft-transmissible microRNA that modulates plant architecture and tuberization in Solanum tuberosum ssp. andigena.
Article in Plant physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 140 papers.
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Who cites it
140 citing papers in PubMed.
- Genome-Wide Identification and Characterization of Thaumatin-Like Proteins in Potato (Solanum tuberosum L.) and Their Role in Stress Tolerance.Molecular biotechnology · 2026Article
- Unraveling the Intertwined Networks of Potato Tuberization: From Epitranscriptomic Signaling to Metabolic Reprogramming.International journal of molecular sciences · 2026Review
- Epigenetic Memory and Hormonal Crosstalk in Plant Drought Adaptation: Mechanisms, miRNAs, and Technological Advances.Epigenomes · 2026Review
- StSP6A: a key regulator integrating multiple signals for potato tuber formation.Plant cell reports · 2026Review
- Molecular mechanisms driving the success of grafting impacted by walnut rootstock.BMC genomics · 2026Article
- Three decades of mobile RNA silencing within plants: what have we learnt?Journal of experimental botany · 2026Review
- Review
- Flowering pathway genes: key targets for accelerated breeding in woody plants.Plant cell reports · 2025Review
- Molecular Pathways Associated with Cold Tolerance in Grafted Cucumber (Plants (Basel, Switzerland) · 2025Article
- Transcriptome-Based miR156-Mediated Expression Dynamics of SPL Transcription Factors During Vegetative to Reproductive Transition in Spinach.Plants (Basel, Switzerland) · 2025Article
- A comprehensive analysis to speculate the role of trithorax genes in photoperiod-mediated tuberization in potato and comparison with storage root crops.BMC plant biology · 2025Article
- Overexpression of StHsfA2 Enhances Thermotolerance and Promotes Tuberisation in Potato Under High Temperature Through StSP6A.Plant biotechnology journal · 2025Article
- Epigenetic crop improvement: Integrating ENCODE strategies into horticultural breeding.Horticulture research · 2025Article
- Rootstock of distant hybrid activates transcription factors of scion cultivar to promote growth and yield in walnut.Plant biotechnology journal · 2025Article
- miR156-SPLs module regulates flowering and controls plant height by modulating gibberellin biosynthesis in citrus.Plant biotechnology journal · 2025Article
- The MIR157-SPL15 module regulates flowering and inflorescence development in Arabidopsis thaliana under short days and in Arabis alpina.PLoS genetics · 2025Article
- MiR5651, miR170-3p, and miR171a-3p Regulate Cadmium Tolerance by TargetingPlants (Basel, Switzerland) · 2025Article
- Redundant functions of miR156-targeted SQUAMOSA PROMOTER BINDING PROTEIN-LIKE transcription factors in promoting cauline leaf identity.The New phytologist · 2025Article
- Regulation of storage organ formation by long-distance tuberigen signals in potato.Horticulture research · 2025Article
- miR156 Is a Negative Regulator of Aluminum Response inPlants (Basel, Switzerland) · 2025Article
80 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MicroRNA156 (miR156) functions in maintaining the juvenile phase in plants. However, the mobility of this microRNA has not been demonstrated. So far, only three microRNAs, miR399, miR395, and miR172, have been shown to be mobile. We demonstrate here that miR156 is a potential graft-transmissible signal that affects plant architecture and tuberization in potato (Solanum tuberosum). Under tuber-noninductive (long-day) conditions, miR156 shows higher abundance in leaves and stems, whereas an increase in abundance of miR156 has been observed in stolons under tuber-inductive (short-day) conditions, indicative of a photoperiodic control. Detection of miR156 in phloem cells of wild-type plants and mobility assays in heterografts suggest that miR156 is a graft-transmissible signal. This movement was correlated with changes in leaf morphology and longer trichomes in leaves. Overexpression of miR156 in potato caused a drastic phenotype resulting in altered plant architecture and reduced tuber yield. miR156 overexpression plants also exhibited altered levels of cytokinin and strigolactone along with increased levels of LONELY GUY1 and StCyclin D3.1 transcripts as compared with wild-type plants. RNA ligase-mediated rapid amplification of complementary DNA ends analysis validated SQUAMOSA PROMOTER BINDING-LIKE3 (StSPL3), StSPL6, StSPL9, StSPL13, and StLIGULELESS1 as targets of miR156. Gel-shift assays indicate the regulation of miR172 by miR156 through StSPL9. miR156-resistant SPL9 overexpression lines exhibited increased miR172 levels under a short-day photoperiod, supporting miR172 regulation via the miR156-SPL9 module. Overall, our results strongly suggest that miR156 is a phloem-mobile signal regulating potato development.
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