Evidence map›Paper›PMID 24351190›Full record

ArticleJournal of diabetes science and technology2013

Algorithms for a closed-loop artificial pancreas: the case for model predictive control.

B Wayne Bequette

Registry-linked trialAbstract readComment
In one paragraph

Article in Journal of diabetes science and technology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03911687 (Communicating Narrative Concerns Entered by RNs), which is not on this map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03911687 nacompletednot on this mapstarted 2020, after this paper: background citation

Communicating Narrative Concerns Entered by RNs (CONCERN) Clinical Decision Support (CDS) System

TypeinterventionalSponsorColumbia UniversityRan2020 to 2022Enrolled60,893ConditionsHospital Acquired ConditionArmsCONCERN CDS system notification
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Article
  9. Article
  10. Review
  11. Algorithms for Automated Insulin Delivery: An Overview.Journal of diabetes science and technology · 2022
    Review
  12. Diabetes Technology Meeting 2021.Journal of diabetes science and technology · 2022
    Article
  13. Article
  14. Article
  15. A New Meal Absorption Model for Artificial Pancreas Systems.Journal of diabetes science and technology · 2022
    Article
  16. Review
  17. Article
  18. Embedded Model Predictive Control for a Wearable Artificial Pancreas.IEEE transactions on control systems technology : a publication of the IEEE Control Systems Society · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

B Wayne BequetteDepartment of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, 110 Eighth Street, Troy, NY 12180-3590. bequette@rpi.edu.

Funding

In home closed loop reduction of nocturnal hypoglycemia and daytime hyperglycemiaR01DK085591 · NIDDK · JAEB CENTER FOR HEALTH RESEARCH, INC. · PI BECK, ROY W., BUCKINGHAM, BRUCE A · 2009 to 2013
$3.9M
NIDDK NIH HHS 5R01DK085591-03
6 · The paper itself

Abstract

The relative merits of model predictive control (MPC) and proportional-integral-derivative (PID) control are discussed, with the end goal of a closed-loop artificial pancreas (AP). It is stressed that neither MPC nor PID are single algorithms, but rather are approaches or strategies that may be implemented very differently by different engineers. The primary advantages to MPC are that (i) constraints on the insulin delivery rate (and/or insulin on board) can be explicitly included in the control calculation; (ii) it is a general framework that makes it relatively easy to include the effect of meals, exercise, and other events that are a function of the time of day; and (iii) it is flexible enough to include many different objectives, from set-point tracking (target) to zone (control to range). In the end, however, it is recognized that the control algorithm, while important, represents only a portion of the effort required to develop a closed-loop AP. Thus, any number of algorithms/approaches can be successful--the engineers involved in the design must have experience with the particular technique, including the important experience of implementing the algorithm in human studies and not simply through simulation studies.

Indexed as

AlgorithmsPancreas, ArtificialDiabetes Mellitus, Type 1Humans

Identifiers

PMID24351190
PMCPMC3876342

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.