ArticleJournal of veterinary internal medicine
Cardiac biomarkers in hyperthyroid cats.
Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Cardiovascular biomarkers in feline hypertrophic cardiomyopathy phenotype: evidence from the last decade.Veterinary research communications · 2026Pooled it
- 2016 AAFP Guidelines for the Management of Feline Hyperthyroidism.Journal of feline medicine and surgery · 2016Guideline
- Feline comorbidities: cardiovascular and kidney diseases.Journal of feline medicine and surgery · 2026Review
- Hypertrophic cardiomyopathy is not the sole echocardiographic phenotype associated with hyperthyroidism in cats: a retrospective study in 147 cats (2005-2025).Journal of veterinary internal medicine · 2026Article
- Analytical validation and clinical evaluation of a high-sensitivity cardiac troponin I immunoassay for use in cats.PloS one · 2026Article
- Cardiac Abnormalities in Feline Hyperthyroidism.Veterinary sciences · 2025Review
- Linking clinical and imaging diagnostic assessments of the feline hypertrophic cardiomyopathy phenotype.Frontiers in veterinary science · 2025Review
- Cardiac Troponin I and Electrocardiographic Evaluation in Hospitalized Cats with Systemic Inflammatory Response Syndrome.Veterinary sciences · 2023Article
- Cardiac troponin I in healthy Norwegian Forest Cat, Birman and domestic shorthair cats, and in cats with hypertrophic cardiomyopathy.Journal of feline medicine and surgery · 2022Article
- The Feline Cardiomyopathies: 1. General concepts.Journal of feline medicine and surgery · 2021Article
- The Feline Cardiomyopathies: 3. Cardiomyopathies other than HCM.Journal of feline medicine and surgery · 2021Article
- The Feline Cardiomyopathies: 2. Hypertrophic cardiomyopathy.Journal of feline medicine and surgery · 2021Article
- Updates on Laboratory Evaluation of Feline Cardiac Diseases.Veterinary sciences · 2021Review
- Accuracy of methods for diagnosing heart diseases in cats.Veterinary world · 2020Article
- Evaluation of a sensitive cardiac troponin I assay as a screening test for the diagnosis of hypertrophic cardiomyopathy in cats.Journal of veterinary internal medicine · 2019Article
- One-year study evaluating efficacy of an iodine-restricted diet for the treatment of moderate-to-severe hyperthyroidism in cats.Veterinary medicine (Auckland, N.Z.) · 2019Article
- Diagnostic utility of cardiac troponin I in cats with hypertrophic cardiomyopathy.Journal of veterinary internal medicine · 2018Article
- Article
- Assessment of a bedside test for N-terminal pro B-type natriuretic peptide (NT-proBNP) to differentiate cardiac from non-cardiac causes of pleural effusion in cats.BMC veterinary research · 2017Article
- A One Health Approach to Hypertrophic Cardiomyopathy.The Yale journal of biology and medicine · 2017Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHyperthyroidism has substantial effects on the circulatory system. The cardiac biomarkers NT-proBNP and troponin I (cTNI) have proven useful in identifying cats with myocardial disease but have not been extensively investigated in hyperthyroidism. HYPOTHESIS: Plasma NT-proBNP and cTNI concentrations are higher in cats with primary myocardial disease than in cats with hyperthyroidism and higher in cats with hyperthyroidism than in healthy control cats. ANIMALS: Twenty-three hyperthyroid cats, 17 cats with subclinical hypertrophic cardiomyopathy (HCM), and 19 euthyroid, normotensive healthy cats ≥8 years of age. Fourteen of the hyperthyroid cats were re-evaluated 3 months after administration of radioiodine ((131)I).
methodsComplete history, physical examination, complete blood count, serum biochemistries, urinalysis, blood pressure measurement, serum T4 concentration, plasma concentrations of NT-proBNP and cTNI, and echocardiogram were obtained prospectively from each cat.
resultsHyperthyroid cats and cats with HCM had plasma NT-proBNP and cTNI concentrations that were significantly higher than those of healthy cats, but there was no significant difference between hyperthyroid cats and cats with HCM with respect to the concentration of either biomarker. In hyperthyroid cats that were re-evaluated 3 months after (131) I treatment, plasma NT-proBNP and cTNI concentrations as well as ventricular wall thickness had decreased significantly. CONCLUSIONS AND CLINICAL IMPORTANCE: Although there may be a role for NT-proBNP in monitoring the cardiac response to treatment of hyperthyroidism, neither NT-proBNP nor cTNI distinguish hypertrophy associated with hyperthyroidism from primary HCM. Therefore, the thyroid status of older cats should be ascertained before interpreting NT-proBNP and cTNI concentrations.
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Registered trials
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