ReviewBioMed research international2013
Topical promethazine side effects: our experience and review of the literature.
Review in BioMed research international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- The epidemiology and phenomenology of non-antipsychotic-induced dystonia: a hybrid systematic-narrative review.European psychiatry : the journal of the Association of European Psychiatrists · 2025Pooled it
- Muscarinic acetylcholine activity modulates cortical silent period, but not motor evoked potentials, during muscle contractions.Experimental brain research · 2023Trial
- Midazolam versus midazolam-promethazine combination for oral sedation in third molar surgery: A randomized split-mouth trial.Medicina oral, patologia oral y cirugia bucal · 2026Article
- Thymol as a Potential Natural Antiemetic: Insights From In Vivo and In Silico Studies.Food science & nutrition · 2025Article
- Synthesis of Phenothiazine Derivatives and their Diverse Biological Activities: A Review.Mini reviews in medicinal chemistry · 2025Review
- Rapid colorimetric sensing of chlorpromazine HCl antipsychotic throughRSC advances · 2024Article
- Green Synthetic Strategies and Pharmaceutical Applications of Thiazine and its Derivatives: An Updated Review.Current pharmaceutical biotechnology · 2024Review
- Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII.Journal of enzyme inhibition and medicinal chemistry · 2023Article
- Nutritional and Behavioral Countermeasures as Medication Approaches to Relieve Motion Sickness: A Comprehensive Review.Nutrients · 2023Review
- Development of the New Sensor Based on Functionalized Carbon Nanomaterials for Promethazine Hydrochloride Determination.Sensors (Basel, Switzerland) · 2023Article
- Role of G-protein coupled receptors in cardiovascular diseases.Frontiers in cardiovascular medicine · 2023Review
- Effect of promethazine in cleft surgeries among Indian children.Bioinformation · 2023Article
- Promethazine hydrochloride reduces children's agitation during ocular examination for trauma.European journal of translational myology · 2022Article
- Article
- Promethazine-induced delirium with perceptual abnormalities: are we thinking broadly when assessing patients?BMJ case reports · 2021Article
- Synergistic Effects of Efflux Pump Modulators on the Azole Antifungal Susceptibility of Microsporum canis.Mycopathologia · 2020Article
- Promethazine exhibits antiparasitic propertiesAntimicrobial agents and chemotherapy · 2019Article
- S(-) and R(+) species derived from antihistaminic promethazine agent: structural and vibrational studies.Heliyon · 2019Article
- Use of Promethazine and Meperidine as Premedicants in Asthmatics before Initiation of Surgery: An Interim Report.Advanced journal of emergency medicine · 2019Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Promethazine hydrochloride is a first-generation H1 receptor antagonist, antihistamine, and antiemetic medication that can also have strong sedative effects. The apparent ability of topical H1r/2r antagonists to target epidermal H1/2r was translated into increased efficacy in the treatment of inflammatory dermatoses, likely due to decreased inflammation and enhanced barrier function.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.