Evidence map›Paper›PMID 24349942›Full record

ArticleWiley interdisciplinary reviews. Membrane transport and signaling2012

P2X receptors in neuroglia.

Alexei Verkhratsky, Yuri Pankratov, Ulyana Lalo, Maiken Nedergaard

Open access · bronzeAbstract read
In one paragraph

Article in Wiley interdisciplinary reviews. Membrane transport and signaling, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Bidirectional Interplay Between Microglia and Mast Cells.International journal of molecular sciences · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Modulation of P2XPhysiological reports · 2022
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Synaptic Pruning by Microglia in Epilepsy.Journal of clinical medicine · 2019
    Review
  17. Article
  18. Folliculin Regulates Osteoclastogenesis Through Metabolic Regulation.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2018
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Alexei VerkhratskyFaculty of Life Sciences, The University of Manchester, Manchester, UK ; IKERBASQUE, Basque Foundation for Science, Bilbao, Spain ; Department of Neurosciences, University of the Basque Country UPV/EHU, Leioa, Spain.
Yuri PankratovSchool of Life Sciences, University of Warwick, Coventry, UK.
Ulyana LaloFaculty of Life Sciences, The University of Manchester, Manchester, UK.
Maiken NedergaardDivision of Glial Disease and Therapeutics, Center for Translational Neuromedicine, Department of Neurosurgery, University of Rochester Medical Center, Rochester, NY, USA.
Ikerbasque · ESUniversity of Manchester · GBUniversity of Rochester Medical Center · USUniversity of Warwick · GB

Funding

Failure of metabolite clearance in a model of multi-lacunar infarctsR01NS078167 · NINDS · UNIVERSITY OF ROCHESTER · PI NEDERGAARD, MAIKEN · 2012 to 2016
$1.8M
The glymphatic system, a new concept in glia biologyR01NS078304 · NINDS · UNIVERSITY OF ROCHESTER · PI NEDERGAARD, MAIKEN · 2012 to 2016
$1.7M
ATP as the instigator of inflammatory responses to spinal cord injuryR01NS075177 · NINDS · UNIVERSITY OF ROCHESTER · PI NEDERGAARD, MAIKEN · 2012 to 2016
$1.6M
NINDS NIH HHS R01 NS075177NINDS NIH HHS R01 NS078167NINDS NIH HHS R01 NS078304
6 · The paper itself

Abstract

Different types of ionotropic P2X purinoceptors are expressed in all major types of neuroglia, where they mediate a variety of physiological and pathological signaling. Cortical astrocytes express specific P2X

Identifiers

PMID24349942
PMCPMC3859444
OpenAlexW2042065841

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.