ArticlePloS one2013
Does ploidy level directly control cell size? Counterevidence from Arabidopsis genetics.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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Who cites it
50 citing papers in PubMed.
- Squamate ventricular cardiomyocytes: Ploidy, proliferation, and heart muscle cell size in the leopard gecko (Eublepharis macularius).Developmental dynamics : an official publication of the American Association of Anatomists · 2025Article
- How Did Evolution Halve Genome Size During an Oceanic Island Colonization?Molecular biology and evolution · 2025Article
- The role of DNA content in shaping chromatin architecture and gene expression.The Plant journal : for cell and molecular biology · 2025Article
- The Effect of Triploidy on Gonadal Development, Hematology and Biochemistry in the European Grayling (Animals : an open access journal from MDPI · 2025Article
- Asymmetric genome merging leads to gene expression novelty through nucleo-cytoplasmic disruptions and transcriptomic shock in Chlamydomonas triploids.The New phytologist · 2025Article
- Transcriptomics and Metabolomics Reveal Biosynthetic Pathways and Regulatory Mechanisms of Phenylpropanes in Different Ploidy ofPlants (Basel, Switzerland) · 2024Article
- APIS: an updated parentage assignment software managing triploids induced from diploid parents.G3 (Bethesda, Md.) · 2024Article
- Polyploidy and mTOR signaling: a possible molecular link.Cell communication and signaling : CCS · 2024Review
- The Abundant and Unique Transcripts and Alternative Splicing of the Artificially Autododecaploid London Plane (International journal of molecular sciences · 2023Article
- The immediate effects of polyploidization ofEvolution letters · 2023Article
- Differences in Leaf Morphology and Related Gene Expression between Diploid and Tetraploid Birch (International journal of molecular sciences · 2022Article
- Dosage-sensitive miRNAs trigger modulation of gene expression during genomic imbalance in maize.Nature communications · 2022Article
- Effect of aneuploidy of a non-essential chromosome on gene expression in maize.The Plant journal : for cell and molecular biology · 2022Article
- Cell biology of the leaf epidermis: Fate specification, morphogenesis, and coordination.The Plant cell · 2022Review
- Integrated Analysis of Hi-C and RNA-Seq Reveals the Molecular Mechanism of Autopolyploid Growth Advantages in Pak Choi (Frontiers in plant science · 2022Article
- Article
- Consequences of whole genome duplication for 2n pollen performance.Plant reproduction · 2021Review
- Genomic imbalance determines positive and negative modulation of gene expression in diploid maize.The Plant cell · 2021Article
- An Arabidopsis AT-hook motif nuclear protein mediates somatic embryogenesis and coinciding genome duplication.Nature communications · 2021Article
- Ploidy influences wheat mesophyll cell geometry, packing and leaf function.Plant direct · 2021Article
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1 author.
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Abstract
Ploidy level affects cell size in many organisms, and ploidy-dependent cell enlargement has been used to breed many useful organisms. However, how polyploidy affects cell size remains unknown. Previous studies have explored changes in transcriptome data caused by polyploidy, but have not been successful. The most naïve theory explaining ploidy-dependent cell enlargement is that increases in gene copy number increase the amount of protein, which in turn increases the cell volume. This hypothesis can be evaluated by examining whether any strains, mutants, or transgenics show the same cell size before and after a tetraploidization event. I performed this experiment by tetraploidizing various mutants and transgenics of Arabidopsis thaliana, which show a wide range in cell size, and found that the ploidy-dependent increase in cell volume is genetically regulated. This result is not in agreement with the theory described above.
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