Trial reportPloS one2013
When, where and how osteoporosis-associated fractures occur: an analysis from the Global Longitudinal Study of Osteoporosis in Women (GLOW).
Trial report in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05541432 (Finding the Optimal Resistance Training Intensity For Your Bones), which is not on this map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Finding the Optimal Resistance Training Intensity For Your Bones: A Randomized Controlled Trial (FORTIFY Bones)
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Orthopaedic, trauma surgery, and Covid-2019 pandemic: clinical panorama and future prospective in Europe.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Pooled it
- Circumstances of fall-related fracture events among men in late life.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- How neighborhood socioeconomic status, green space, and walkability are associated with risk for fracture among postmenopausal women.JBMR plus · 2025Article
- Article
- Among people on osteoporosis medication, loss of appendicular or total body lean mass is an independent risk factor for hip and major osteoporotic fractures.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024Article
- Cyclic testing of standalone ALIF versus TLIF in lumbosacral spines of low bone mineral density: an ex vivo biomechanical study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Article
- Polypharmacy of Older Surgical Patients With Extremity Fractures.Geriatric orthopaedic surgery & rehabilitation · 2024Article
- [Osteoporotic vertebral body fractures].Orthopadie (Heidelberg, Germany) · 2023Review
- Ethnic determinants of skeletal health in female patients with fragility fracture in a culturally diverse population.Bone reports · 2023Article
- Effects of COVID-19 confinement on the incidence and mortality of major osteoporotic fractures: an observational study in Catalonia, Spain.Archives of osteoporosis · 2022Observational
- Analysis of Hip Fractures in France During the First COVID-19 Lockdown in Spring 2020.JAMA network open · 2021Article
- Vertebral Fractures in Ireland: A Sub-analysis of the DXA HIP Project.Calcified tissue international · 2021Article
- Impact of confinement during the SARS-CoV-2 pandemic on the incidence of fragility fracture.Medicina clinica (English ed.) · 2021Article
- The impact of lockdown during the COVID-19 pandemic on osteoporotic fragility fractures: an observational study.Archives of osteoporosis · 2020Observational
- Hip Fractures in Older Adults in Ontario, Canada-Monthly Variation, Insights, and Implications.Canadian geriatrics journal : CGJ · 2019Article
- A multiscale model to predict current absolute risk of femoral fracture in a postmenopausal population.Biomechanics and modeling in mechanobiology · 2019Article
- Functional risk for fracture by safe functional motion testing: a short version of the safe functional motion test.Therapeutic advances in musculoskeletal disease · 2019Article
- Risk of post-discharge fall-related injuries among adult patients with syncope: A nationwide cohort study.PloS one · 2018Article
- Bone Phenotype Assessed by HRpQCT and Associations with Fracture Risk in the GLOW Study.Calcified tissue international · 2018Article
- Is the association between hip fractures and seasonality modified by influenza vaccination? An ecological study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors.
Funding
Abstract
objectiveTo examine when, where and how fractures occur in postmenopausal women.
methodsWe analyzed data from the Global Longitudinal Study of Osteoporosis in Women (GLOW), including women aged ≥55 years from the United States of America, Canada, Australia and seven European countries. Women completed questionnaires including fracture data at baseline and years 1, 2 and 3.
resultsAmong 60,393 postmenopausal women, 4122 incident fractures were reported (86% non-hip, non-vertebral [NHNV], 8% presumably clinical vertebral and 6% hip). Hip fractures were more likely to occur in spring, with little seasonal variation for NHNV or spine fractures. Hip fractures occurred equally inside or outside the home, whereas 65% of NHNV fractures occurred outside and 61% of vertebral fractures occurred inside the home. Falls preceded 68-86% of NHNV and 68-83% of hip fractures among women aged ≤64 to ≥85 years, increasing with age. About 45% of vertebral fractures were associated with falls in all age groups except those ≥85 years, when only 24% occurred after falling.
conclusionIn this multi-national cohort, fractures occurred throughout the year, with only hip fracture having a seasonal variation, with a higher proportion in spring. Hip fractures occurred equally within and outside the home, spine fractures more often in the home, and NHNV fractures outside the home. Falls were a proximate cause of most hip and NHNV fractures. Postmenopausal women at risk for fracture need counseling about reducing potentially modifiable fracture risk factors, particularly falls both inside and outside the home and during all seasons of the year.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.