SynthesisPloS one2013
The effectiveness of acupuncture in prevention and treatment of postoperative nausea and vomiting--a systematic review and meta-analysis.
Synthesis in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06633666 (Acupuncture for Long COVID Neuropsychiatric Symptoms), which is not on this map. Cited by 45 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Acupuncture for Long COVID Neuropsychiatric Symptoms: a Pragmatic,Randomized Clinical Trial
Who cites it
45 citing papers in PubMed, 3 syntheses or guidelines pooled it, 123 citations in OpenAlex.
- Suggested Electroacupuncture for Postoperative Nausea and Vomiting: A Comprehensive Meta-Analysis and Systematic Review of Randomized Controlled Trials.Medical science monitor : international medical journal of experimental and clinical research · 2023Pooled it
- Naturopathic Treatment and Complementary Medicine in Surgical Practice.Deutsches Arzteblatt international · 2018Pooled it
- Stimulation of the wrist acupuncture point PC6 for preventing postoperative nausea and vomiting.The Cochrane database of systematic reviews · 2015Pooled it
- Transcutaneous Electrical Acupoint Stimulation Improves Postoperative Nutrition and Promotes Early Recovery of Gastrointestinal Function in Patients with Colorectal Cancer.Combinatorial chemistry & high throughput screening · 2025Trial
- Acupuncture reduces the time from extubation to 'ready for discharge' from the post anaesthesia care unit: results from the randomised controlled AcuARP trial.Scientific reports · 2018Trial
- Trial
- [Effect of acupuncture on the prevention of nausea and vomiting after laparoscopic cholecystectomy: a randomized clinical trial].Brazilian journal of anesthesiology (Elsevier)Trial
- Article
- Acupuncture for patients with Cancer in a Japanese palliative care team: A prospective case series study.Integrative medicine research · 2026Article
- Postoperative nausea and vomiting: current concepts, management strategies, and future perspectives.Frontiers in pharmacology · 2026Review
- Influence of Hypnosis and Acupuncture on Perioperative Complications.Healthcare (Basel, Switzerland) · 2025Article
- Article
- Impact of transcutaneous electrical acupoint stimulation combined with aromatherapy on postoperative nausea and vomiting in patients undergoing microvascular decompression surgery: A prospective randomized study.Journal of anesthesia and translational medicine · 2025Article
- Clinical trial effects of acupuncture combined with different general anesthesia on postoperative nausea and vomiting and early recovery after thyroidectomy with intra-operative neuromonitoring: a randomized controlled trial.Frontiers in medicine · 2025Article
- A Bibliometric Analysis of Acupuncture Treatment of Postoperative Complications from 2003 to 2023.Journal of multidisciplinary healthcare · 2025Review
- Dysmenorrhea, a Narrative Review of Therapeutic Options.Journal of pain research · 2024Review
- Can acupuncture increase microcirculation in peripheral artery disease and diabetic foot syndrome? - a pilot study.Frontiers in medicine · 2024Article
- Esophageal Motility in Patients with Achalasia After Acupuncture.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023Article
- The Effect of Transcutaneous Electrical Acupoint Stimulation on High-Risk Patients with PONV Undergoing Laparoscopic Gynecologic Surgery: A Randomized Controlled Trial.Journal of clinical medicine · 2023Article
- Research Status and Prospects of Acupuncture in Perioperative Medicine Over the Past Decade: A Bibliometric Analysis.Journal of pain research · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcupuncture therapy for preventive and treatment of postoperative nausea and vomiting(PONV), a condition which commonly present after anaesthesia and surgery is a subject of growing interest.
objectiveThis paper included a systematic review and meta-analysis on the effect of different type of acupuncture and acupoint selection in PONV prevention and treatment.
methodsRandomised controlled trials(RCTs) comparing acupuncture with non-acupuncture treatment were identified from databases PubMed, Cochrane, EBSCO, Ovid, CNKI and Wanfangdata. Meta-analysis on eligible studies was performed using fixed-effects model with RevMan 5.2. Results were expressed as RR for dichotomous data, with 95%CI.
resultsThirty RCTs, 1276 patients (intervention) and 1258 patients (control) were identified. Meta-analysis showed that PC6 acupuncture significantly reduced the number of cases of early vomiting (postoperative 0-6h) (RR=0.36, 95%CI 0.19,0.71; P=0.003) and nausea (postoperative 0-24h) (RR=0.25, 95%CI 0.10,0.61; P=0.002), but not early nausea (postoperative 0-6h) (RR=0.64, 95%CI 0.34,1.19; P=0.150) and vomiting (postoperative 0-24h) (RR=0.82, 95%CI 0.48,1.38; P=0.450). PC6 acupressure significantly reduced the number of cases of nausea (RR=0.71, 95%CI 0.57,0.87; P=0.001) and vomiting (RR=0.62, 95%CI 0.49,0.80; P=0.000) at postoperative 0-24h. PC6 electro-acupoint stimulation significantly reduced the number of cases of nausea (RR=0.49, 95%CI 0.38,0.63; P<0.000) and vomiting (RR=0.50, 95%CI 0.36,0.70; P<0.000) at postoperative 0-24h. Stimulation of PC6 with other acupoint(s) significantly reduced the number of cases of nausea and vomiting (RR=0.29, 95%CI 0.17,0.49; P<0.000) at postoperative 0-24h. Stimulation of other acupoint(s)(non PC6) also significantly reduced the number of cases of nausea and vomiting (RR=0.63, 95%CI 0.49,0.81; P=0.000) at postoperative 0-24h. However, the quality of study was generally low in studies of PC6 combined with other acupoint(s) and other acupoint(s). Details of blinding were not reported in most reports.
conclusionsBesides PC6, PC6 combined with other acupoint(s) and other alternative acupoint(s) might be beneficial in prevention and treatment of PONV, the evidence justifies future high-quality studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.