SynthesisPloS one2013
Risk of obstructive sleep apnea in Parkinson's disease: a meta-analysis.
Synthesis in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- Association between glaucoma and obstructive sleep apnea syndrome: a meta-analysis and systematic review.PloS one · 2015Pooled it
- Associations Between Sleep and Non-Motor Symptoms in RBD-Screened Suspected Prodromal Parkinson's Disease with Hyposmia or Orthostatic Hypotension.Journal of clinical medicine · 2026Article
- The Prevalence and Characteristics of Obstructive Sleep Apnea Among Patients With Multiple Sclerosis: A Systematic Review and Meta-Analysis.Journal of central nervous system disease · 2026Article
- Meta-analysis of the prevalence of obstructive sleep apnea and associated risk factors among Parkinson's disease.Sleep and biological rhythms · 2025Review
- Sleep disorders in Parkinson's disease, an early and multiple problem.NPJ Parkinson's disease · 2024Article
- Body mass index and sleep disturbances: a systematic review and meta-analysis.Postepy psychiatrii neurologii · 2023Review
- Association of sleep abnormalities in older adults with risk of developing Parkinson's disease.Sleep · 2022Article
- A Review of a Recent Meta-Analysis Study on Obstructive Sleep Apnea.Journal of rhinology : official journal of the Korean Rhinologic Society · 2022Review
- Respiratory Abnormalities in Parkinson's Disease: What Do We Know from Studies in Humans and Animal Models?International journal of molecular sciences · 2022Review
- Uvulopalatopharyngoplasty may decrease the incidence of Parkinson's disease associated with obstructive sleep apnea.Scientific reports · 2021Article
- Parkinson's disease and obstructive sleep apnea.EXCLI journal · 2021Article
- Sleep Issues in Parkinson's Disease and Their Management.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2020Review
- A mysterious case of an elevated dome of the right diaphragm.Breathe (Sheffield, England) · 2020Article
- Obstructive Sleep Apnea in Neurodegenerative Disorders: Current Evidence in Support of Benefit from Sleep Apnea Treatment.Journal of clinical medicine · 2020Review
- Sleep Disturbances in the Prodromal Stage of Parkinson Disease.Current treatment options in neurology · 2017Review
- Neurological Deficits in Obstructive Sleep Apnea.Current treatment options in neurology · 2017Review
- Impact of concomitant medications on obstructive sleep apnoea.British journal of clinical pharmacology · 2017Review
- A Pilot Study Assessing the Effects of Pallidal Deep Brain Stimulation on Sleep Quality and Polysomnography in Parkinson's Patients.Neuromodulation : journal of the International Neuromodulation Society · 2016Article
- Sleep Dysfunction in Parkinson's Disease.Journal of clinical and diagnostic research : JCDR · 2016Article
- Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesSleep disorders are a common symptom of Parkinson's disease (PD) and they significantly impair the sleep quality of the PD patients. However, there is no conclusive evidence to support the relation between PD and the prevalence of obstructive sleep apnea (OSA). The purpose of this meta-analysis review is to evaluate the association between PD and the prevalence of OSA.
methodsA comprehensive literature search was conducted on PubMed and Embase through July 2013. Only studies that referred to PD and the prevalence of OSA and that met the selection criteria were included in the analysis. The odds ratios (ORs) were used to evaluate the relationship of PD and the prevalence of OSA by the fixed-effect model.
resultsFive eligible studies were analyzed in this study including 322 cases and 6,361 controls. The pooled-analysis showed the OR to be 0.60 (95% confidence interval (CI): 0.44 to 0.81, P = 0.001) and I(2) = 0.0% (χ(2) = 3.90, P = 0.420) in the fixed-effect model.
conclusionsAlthough we only included five small sample studies that indicated high homogeneity in the heterogeneity test, the results suggest that there is a significant negative association between PD and the prevalence of OSA; PD patients generally have a reduced prevalence of OSA. According to our analysis, these results are primarily due to the lower BMI of PD patients when compared with the general population controls.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.