ArticleOncology letters2014
Prognostic factors associated with locally recurrent rectal cancer following primary surgery (Review).
Article in Oncology letters, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Preoperative radiotherapy and curative surgery for the management of localised rectal carcinoma.The Cochrane database of systematic reviews · 2018Pooled it
- Local recurrence in rectal cancer: from detection to structured reporting.Abdominal radiology (New York) · 2026Article
- The Role of Pelvic Reirradiation in the Treatment of Locally Recurrent Rectal Cancer: A Systematic Review.Biomedicines · 2026Review
- Machine learning prognosis model for locally recurrent rectal cancer patients after radioactiveScientific reports · 2025Article
- Identifying baseline rectal MRI features as predictive indicators for local recurrence and metastatic disease in rectal cancer treated with surgical resection and neoadjuvant therapy or surgical resection alone.European journal of radiology · 2025Article
- Roles of MRI evaluation of pelvic recurrence in patients with rectal cancer.Insights into imaging · 2024Article
- Cumulative Incidence, Risk Factors, and Overall Survival of Disease Recurrence after Curative Resection of Stage II-III Colorectal Cancer: A Population-based Study.Cancer research communications · 2024Article
- Locally Recurrent Rectal Cancer: Toward a Second Chance at Cure? A Population-Based, Retrospective Cohort Study.Annals of surgical oncology · 2023Article
- Rectal cancer pelvic recurrence: imaging patterns and key concepts to guide treatment planning.Abdominal radiology (New York) · 2023Review
- Prognostic Factors of Recurrence and Survival in Operated Patients with Colorectal Cancer.Middle East journal of digestive diseases · 2022Article
- Prognostic Factors and Treatment of Recurrence after Local Excision of Rectal Cancer.Yonsei medical journal · 2021Observational
- Whole-exome sequencing of rectal cancer identifies locally recurrent mutations in the Wnt pathway.Aging · 2021Article
- A Case with Rectal Cancer Relapses After Clinical Complete Remission Following Neoadjuvant Chemoradiotherapy.Cancer management and research · 2019Article
- Squamous cell carcinoma of the rectum: Practice trends and patient survival.Cancer medicine · 2018Article
- Local Cancer Recurrence: The Realities, Challenges, and Opportunities for New Therapies.CA: a cancer journal for clinicians · 2018Review
- Long-term outcomes of neoadjuvant-synchronous S-1 plus radiotherapy for locally advanced rectal cancer: a multi-institutional prospective phase II study.Journal of the anus, rectum and colon · 2018Article
- The importance of a multidisciplinary team in rectal cancer management.Clujul medical (1957) · 2017Article
- Focal adhesion kinase: predictor of tumour response and risk factor for recurrence after neoadjuvant chemoradiation in rectal cancer.Journal of cellular and molecular medicine · 2016Article
- Recurrences in stage II rectal carcinoma after curative resection alone: from the viewpoint of angiogenesis.World journal of surgical oncology · 2016Article
- Impact of anatomic location on locally recurrent rectal cancer: superior outcome for intraluminal tumour recurrence.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2015Observational
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Locally recurrent rectal cancer (LRRC) is defined as an intrapelvic recurrence following a primary rectal cancer resection, with or without distal metastasis. The treatment of LRRC remains a clinical challenge. LRRC has been regarded as an incurable disease state leading to a poor quality of life and a limited survival time. However, curative reoperations have proved beneficial for treating LRRC. A complete resection of recurrent tumors (R0 resection) allows the treatment to be curative rather than palliative, which is a milestone in medicine. In LRRC cases, the difficulty of achieving an R0 resection is associated with the post-operative prognosis and is affected by several clinical factors, including the staging of the local recurrence (LR), accompanying symptoms, patterns of tumors and combined therapy. The risk factors following primary surgery that lead to an increased rate of LR are summarized in this study, including the surgical, pathological and therapeutic factors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.