ReviewFrontiers in endocrinology2013
Normal glucose metabolism in carnivores overlaps with diabetes pathology in non-carnivores.
Review in Frontiers in endocrinology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 59 citations in OpenAlex.
- Evaluation of Serum Homocysteine and High-Sensitivity Cardiac Troponins in Cats with Hepatic Lipidosis: An Observational Clinical Study.Veterinary sciences · 2026Article
- Guidelines for nutritional management of feline diabetes mellitus: a proposed classification system integrating medical considerations.Journal of feline medicine and surgery · 2026Review
- Neanderthals, hypercarnivores, and maggots: Insights from stable nitrogen isotopes.Science advances · 2025Article
- Convergent relaxation of molecular constraint in herbivores reveals the changing role of liver and kidney functions across mammalian diets.Genome research · 2024Article
- Nutrient Digestive Bypass: Determinants and Associations with Stool Quality in Cats and Dogs.Animals : an open access journal from MDPI · 2024Article
- In-depth correlation analysis between tear glucose and blood glucose using a wireless smart contact lens.Nature communications · 2024Article
- Refining Convergent Rate Analysis with Topology in Mammalian Longevity and Marine Transitions.Molecular biology and evolution · 2021Article
- Characteristics of PhysiologicalFrontiers in veterinary science · 2021Article
- Insights into Body Size Evolution: A Comparative Transcriptome Study on Three Species of Asian Sisoridae Catfish.International journal of molecular sciences · 2019Article
- Convergent gene losses illuminate metabolic and physiological changes in herbivores and carnivores.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Paracrine Interactions within the Pancreatic Islet Determine the Glycemic Set Point.Cell metabolism · 2018Article
- Article
- Cats and Carbohydrates: The Carnivore Fantasy?Veterinary sciences · 2017Review
- Human heart failure with preserved ejection versus feline cardiomyopathy: what can we learn from both veterinary and human medicine?Heart failure reviews · 2017Review
- Obtaining accurate glucose measurements from wild animals under field conditions: comparing a hand held glucometer with a standard laboratory technique in grey seals.Conservation physiology · 2017Article
- Comparison of carnivore, omnivore, and herbivore mammalian genomes with a new leopard assembly.Genome biology · 2016Article
- Physiological handling of dietary fructose-containing sugars: implications for health.International journal of obesity (2005) · 2016Review
- Dolphins and diabetes: applying one health for breakthrough discoveries.Frontiers in endocrinology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Carnivores, such as the dolphin and the domestic cat, have numerous adaptations that befit consumption of diets with high protein and fat content, with little carbohydrate content. Consequently, nutrient metabolism in carnivorous species differs substantially from that of non-carnivores. Important metabolic pathways known to differ between carnivores and non-carnivores are implicated in the development of diabetes and insulin resistance in non-carnivores: (1) the hepatic glucokinase (GCK) pathway is absent in healthy carnivores yet GCK deficiency may result in diabetes in rodents and humans, (2) healthy dolphins and cats are prone to periods of fasting hyperglycemia and exhibit insulin resistance, both of which are risk factors for diabetes in non-carnivores. Similarly, carnivores develop naturally occurring diseases such as hemochromatosis, fatty liver, obesity, and diabetes that have strong parallels with the same disorders in humans. Understanding how evolution, environment, diet, and domestication may play a role with nutrient metabolism in the dolphin and cat may also be relevant to human diabetes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.