ArticleFrontiers in systems neuroscience2013
Unilateral hearing during development: hemispheric specificity in plastic reorganizations.
Article in Frontiers in systems neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed.
- Effects of Cochlear Implantation on Binaural Hearing in Adults With Unilateral Hearing Loss.Trends in hearingTrial
- A tale of two ears: development of binaural auditory processing in the big brown bat.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026Article
- Spatial hearing adaptation in congenital and acquired single-sided deafness.Frontiers in neuroscience · 2026Article
- Hearing Outcomes in Children with Unilateral Hearing Loss. The Benefits of Rehabilitative Strategies: Preliminary Results.Audiology research · 2025Article
- Association between cortical auditory evoked potentials recorded directly through cochlear implants and post-implantation auditory and speech outcomes.Frontiers in neuroscience · 2025Article
- Dissociated Representation of Binaural Cues in Single-Sided Deafness: Implications for Cochlear Implantation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Single-Sided Deafness and Hearing Rehabilitation Modalities: Contralateral Routing of Signal Devices, Bone Conduction Devices, and Cochlear Implants.Brain sciences · 2024Review
- Bidirectional remodeling of the central auditory system caused by unilateral auditory deprivation.Frontiers in neurology · 2024Review
- Cortical imbalance following delayed restoration of bilateral hearing in deaf adolescents.Human brain mapping · 2022Article
- Deficient Recurrent Cortical Processing in Congenital Deafness.Frontiers in systems neuroscience · 2022Article
- Dichotic listening performance with cochlear-implant simulations of ear asymmetry is consistent with difficulty ignoring clearer speech.Attention, perception & psychophysics · 2021Article
- Changes in the Gene Expression Profiles of the Inferior Colliculus Following Unilateral Cochlear Ablation in Adult Rats.Biochemical genetics · 2021Article
- Ear-Specific Hemispheric Asymmetry in Unilateral Deafness Revealed by Auditory Cortical Activity.Frontiers in neuroscience · 2021Article
- A Porcine Congenital Single-Sided Deafness Model, Its Population Statistics and Degenerative Changes.Frontiers in cell and developmental biology · 2021Article
- Cortical Regions Activated by Spectrally Degraded Speech in Adults With Single Sided Deafness or Bilateral Normal Hearing.Frontiers in neuroscience · 2021Article
- Toward Optimal Care for Children With Congenital Unilateral Aural Atresia.Frontiers in neurology · 2021Article
- Cochlear Implants in Single-Sided Deafness. Comparison Between Children and Adult Populations With Post-lingually Acquired Severe to Profound Hearing Loss.Frontiers in neurology · 2021Article
- Bilateral Cochlear Implants or Bimodal Hearing for Children with Bilateral Sensorineural Hearing Loss.Current otorhinolaryngology reports · 2020Article
- Speech Perception Changes in the Acoustically Aided, Nonimplanted Ear after Cochlear Implantation: A Multicenter Study.Journal of clinical medicine · 2020Article
- Research Insights on Neural Effects of Auditory Deprivation and Restoration in Unilateral Hearing Loss: A Systematic Review.Journal of clinical medicine · 2020Review
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Authors and funding
4 authors.
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Abstract
The present study investigates the hemispheric contributions of neuronal reorganization following early single-sided hearing (unilateral deafness). The experiments were performed on ten cats from our colony of deaf white cats. Two were identified in early hearing screening as unilaterally congenitally deaf. The remaining eight were bilaterally congenitally deaf, unilaterally implanted at different ages with a cochlear implant. Implanted animals were chronically stimulated using a single-channel portable signal processor for two to five months. Microelectrode recordings were performed at the primary auditory cortex under stimulation at the hearing and deaf ear with bilateral cochlear implants. Local field potentials (LFPs) were compared at the cortex ipsilateral and contralateral to the hearing ear. The focus of the study was on the morphology and the onset latency of the LFPs. With respect to morphology of LFPs, pronounced hemisphere-specific effects were observed. Morphology of amplitude-normalized LFPs for stimulation of the deaf and the hearing ear was similar for responses recorded at the same hemisphere. However, when comparisons were performed between the hemispheres, the morphology was more dissimilar even though the same ear was stimulated. This demonstrates hemispheric specificity of some cortical adaptations irrespective of the ear stimulated. The results suggest a specific adaptation process at the hemisphere ipsilateral to the hearing ear, involving specific (down-regulated inhibitory) mechanisms not found in the contralateral hemisphere. Finally, onset latencies revealed that the sensitive period for the cortex ipsilateral to the hearing ear is shorter than that for the contralateral cortex. Unilateral hearing experience leads to a functionally-asymmetric brain with different neuronal reorganizations and different sensitive periods involved.
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