ArticleVascular health and risk management2013
Serum lipid profile and correlates in newly presenting Nigerians with arterial hypertension.
Article in Vascular health and risk management, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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12 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Effects of L-carnitine supplementation on blood pressure: a systematic review and meta-analysis of randomized controlled trials.Journal of human hypertension · 2019Pooled it
- Association of cardio-ankle vascular index value with cardiovascular risk factors in elderly individuals.International journal of cardiology. Heart & vasculature · 2026Article
- Characteristics of serum lipid levels in patients with hypertension: a hospital-based retrospective descriptive study.BMJ open · 2022Article
- Patterns of dyslipidemia amongst hypertensive patients in Abuja, North Central Nigeria.The Pan African medical journal · 2021Article
- The relationship between measures of obesity and atherogenic lipids among Nigerians with hypertension.Malawi medical journal : the journal of Medical Association of Malawi · 2019Article
- The burden of dyslipidaemia and factors associated with lipid levels among adults in rural northern Ghana: An AWI-Gen sub-study.PloS one · 2018Article
- Modifiable lifestyle risk factors for stroke among a high risk hypertensive population in Greater Kampala, Uganda; a cross-sectional study.BMC research notes · 2017Article
- Cardiovascular risk factors in adult general out-patient clinics in Nigeria: a country analysis of the Africa and Middle East Cardiovascular Epidemiological (ACE) study.African health sciences · 2017Article
- Optimal serum cholesterol concentrations are associated with accelerated bone loss in African ancestry men.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016Article
- Relationship between cardio-ankle vascular index and plasma lipids in hypertension subjects.Journal of human hypertension · 2015Article
- The approach of general practitioners in Lagos to the detection and evaluation of hypertension.Clinical hypertension · 2015Article
- Awareness of hypertension guidelines and the diagnosis and evaluation of hypertension by primary care physicians in Nigeria.Cardiovascular journal of AfricaArticle
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Authors and funding
6 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundArterial hypertension and dyslipidemia are modifiable cardiovascular risk factors. The multiplicative effect of these risk factors may worsen the atherogenic index of an individual. The objective of this study was to determine the pattern and prevalence of dyslipidemia in newly presenting Nigerians with arterial hypertension, as well as determine some of its correlates.
methodsThis cross-sectional study compared 115 newly presenting, age- and sex-matched individuals with arterial hypertension with 115 normotensive individuals. Fasting lipids, total cholesterol (TC), triglycerides, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and fasting plasma glucose were estimated.
resultsPatients with arterial hypertension had higher body mass index (t=7.64; P=0.000), TC (t=2.95; P=0.006), and HDL-C (t=-5.18; P=0.000). The most common dyslipidemia was low HDL-C, found in both the hypertensive (44.3%) and normotensive (20.9%) patients. The prevalence of dyslipidemia in hypertensives and controls was 64% and 39%, respectively. In hypertensive patients, TC correlated positively to diastolic blood pressure (r=0.218; P=0.0019). Other positive correlates include LDL-C and age (r=0.217; P=0.020) and fasting plasma glucose (r=0.202; P=0.030) and body mass index (r=0.209; P=0.025). Among normotensive controls, TC correlated positively with LDL-C (r=0.63; P=0.000) but correlated negatively with tri glycerides (r=-0.30; P=0.001).
conclusionLipid abnormalities are common in newly presenting Nigerians with arterial hypertension. Screening of these risk factors, promotion of healthy lifestyle, and the institution of therapy is desirable to reduce their multiplicative effects.
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