Evidence map›Paper›PMID 24347829›Full record

ReviewMediators of inflammation2013

Systemic treatments for noninfectious vitreous inflammation.

Angela Jiang, Jillian Wang, Malav Joshi, John Byron Christoforidis

Abstract readReview
In one paragraph

Review in Mediators of inflammation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Nanomedicine in the application of uveal melanoma.International journal of ophthalmology · 2016
    Review
  2. Article
  3. Pharmacokinetics, electrophysiological, and morphological effects of the intravitreal injection of mycophenolic acid in rabbits.Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Angela JiangDepartment of Ophthalmology, The Ohio State University Wexner Medical Center, 915 Olentangy River Road, Suite 5000, Columbus, OH 43212, USA.
Jillian WangDepartment of Ophthalmology, The Ohio State University Wexner Medical Center, 915 Olentangy River Road, Suite 5000, Columbus, OH 43212, USA.
Malav JoshiDepartment of Ophthalmology, The University of Arizona Medical Center, 655 North Alvernon Way, Suite 108, Tucson, AZ 85711, USA.
John Byron ChristoforidisDepartment of Ophthalmology, The University of Arizona Medical Center, 655 North Alvernon Way, Suite 108, Tucson, AZ 85711, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitreous inflammation, or vitritis, may result from many causes, including both infectious and noninfectious, including rheumatologic and autoimmune processes. Vitritis is commonly vision threatening and has serious sequelae. Treatment is frequently challenging, but, today, there are multiple methods of systemic treatment for vitritis. These categories include corticosteroids, antimetabolites, alkylating agents, T-cell inhibitors/calcineurin inhibitors, and biologic agents. These treatment categories were reviewed last year, but, even over the course of just a year, many therapies have made progress, as we have learned more about their indications and efficacy. We discuss here discoveries made over the past year on both existing and new drugs, as well as reviewing mechanisms of action, clinical dosages, specific conditions that are treated, adverse effects, and usual course of treatment for each class of therapy.

Indexed as

AdalimumabAdrenal Cortex HormonesAntibodies, Monoclonal, HumanizedEye DiseasesHumansImmunosuppressive AgentsInflammationIsoxazolesLeflunomideVitreous BodyAdalimumabAdrenal Cortex HormonesAntibodies, Monoclonal, HumanizedImmunosuppressive AgentsIsoxazolesLeflunomidetocilizumab

Identifiers

PMID24347829
PMCPMC3853923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.