SynthesisTumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine2014
Allergic conditions reduce the risk of glioma: a meta-analysis based on 128,936 subjects.
Synthesis in Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- The association between allergy and risk of brain tumors: Evidence from 40 observational studies.Acta neurochirurgica · 2025Pooled it
- Partitioned glioma heritability shows subtype-specific enrichment in immune cells.Neuro-oncology · 2021Pooled it
- Inverse Association between Prediagnostic IgE Levels and the Risk of Brain Tumors: A Systematic Review and Meta-Analysis.BioMed research international · 2015Pooled it
- The Association between Allergy and Cancer: A Case-Control Study.Asian Pacific journal of cancer prevention : APJCP · 2024Article
- Life-style and metabolic factors do not affect risk for glioma: a prospective population-based study (The Cohort of Norway).Frontiers in oncology · 2024Article
- History of atopy confers improved outcomes in IDH mutant and wildtype lower grade gliomas.Journal of neuro-oncology · 2021Article
- Insights from IgE Immune Surveillance in Allergy and Cancer for Anti-Tumour IgE Treatments.Cancers · 2021Review
- Autoimmune diseases and immunosuppressive therapy in relation to the risk of glioma.Cancer medicine · 2020Article
- AllergoOncology: High innate IgE levels are decisive for the survival of cancer-bearing mice.The World Allergy Organization journal · 2019Article
- Allergic conditions and risk of glioma and meningioma in the CERENAT case-control study.Journal of neuro-oncology · 2018Article
- Use of MendelianFrontiers in genetics · 2018Review
- Opportunities During Early Life for Cancer Prevention: Highlights From a Series of Virtual Meetings With Experts.Pediatrics · 2016Article
- Associations between allergic conditions and pediatric brain tumors in Neurofibromatosis type 1.Familial cancer · 2016Article
- Approaching a Scientific Consensus on the Association between Allergies and Glioma Risk: A Report from the Glioma International Case-Control Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2016Article
- Article
- Analysis of the involvement of cytokines in allergy and breast cancer association.Contemporary oncology (Poznan, Poland) · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many studies have investigated the association between the allergic conditions and the risk of glioma. However, the evidence is inadequate to draw robust conclusions because most studies were generally small and conducted in heterogeneous populations. To shed light on these inconclusive findings, we conducted a meta-analysis of studies relating the allergic conditions to the risk of glioma. We identified the relevant studies by searching ISI Web of Science, PubMed, EMBASE, Chinese National Knowledge Infrastructure (CNKI) databases, and Wanfang database by October 2013. We included studies that reported odds ratio (OR) or hazard ratio (HR) with its 95% confidence interval (CI) for the association between the allergic condition and the risk of glioma. Eighteen independent publications, with 9,986 glioma cases and 118,950 controls, were included. Our results showed that allergic condition was reversely associated with the risk of glioma (OR = 0.78, 95% CI 0.73-0.83, P < 0.001). The results of our meta-analysis indicated that allergic conditions significantly reduce the risk of glioma.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.