ArticleObesity surgery2014
Evolution of subclinical hypothyroidism and its relation with glucose and triglycerides levels in morbidly obese patients after undergoing sleeve gastrectomy as bariatric procedure.
Article in Obesity surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Time Trends in Thyroid Hormone Changes Following Bariatric Surgery: A Systematic Review and Meta-Analysis.Obesity surgery · 2026Pooled it
- Thyroid function post-bariatric surgery: an updated systematic review and meta-analysis.Obesity surgery · 2025Pooled it
- Effect of Bariatric Surgery on Thyroid Function in Obese Patients: a Systematic Review and Meta-Analysis.Obesity surgery · 2017Pooled it
- New association of bone morphogenetic protein 4 concentrations with fat distribution in obesity and Exenatide intervention on it.Lipids in health and disease · 2017Trial
- Obesity-related thyroid reflections: from weight gain to weight loss.European thyroid journal · 2026Review
- The impact of weight loss interventions on thyroid function: a systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2025Review
- Total weight loss induces the alteration in thyroid function after bariatric surgery.Frontiers in endocrinology · 2024Article
- The Impact of Laparoscopic Sleeve Gastrectomy on Thyroid Functions in Egyptian Patients with Obesity.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023Article
- Laparoscopic Sleeve Gastrectomy has A Positive Impact on Subclinical Hypothyroidism Among Obese Patients: A Prospective Study.World journal of surgery · 2021Article
- The Effect of Laparoscopic Sleeve Gastrectomy on Serum Thyroid-Stimulating Hormone Levels in Obese Patients with Overt and Subclinical Hypothyroidism: a 7-Year Retrospective Study.Obesity surgery · 2020Article
- Reduction in Thyroid-Stimulating Hormone Correlated with Improved Inflammation Markers in Chinese Patients with Morbid Obesity Undergoing Laparoscopic Sleeve Gastrectomy.Obesity surgery · 2019Article
- Preoperative thyroid function and weight loss after bariatric surgery.International journal of obesity (2005) · 2019Article
- Sex Differences in the Associations of Obesity With Hypothyroidism and Thyroid Autoimmunity Among Chinese Adults.Frontiers in physiology · 2018Article
- Comparative study of outcomes following laparoscopic Roux-en-Y gastric bypass and sleeve gastrectomy in morbidly obese patients: A case control study.World journal of gastrointestinal endoscopy · 2017Article
- Elevated thyroid stimulating hormone levels are associated with metabolic syndrome in a Chinese community-based population of euthyroid people aged 40 years and olderJournal of biomedical research · 2016Article
- Thyroid-Stimulating Hormone Increases HNF-4α Phosphorylation via cAMP/PKA Pathway in the Liver.Scientific reports · 2015Article
- Subclinical hypothyroidism: a historical view and shifting prevalence.International journal of clinical practice · 2015Review
- Bone health and clinical results after hip fracture surgery in patients with subclinical hypothyroidism.Journal of bone metabolism · 2014Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is an increased prevalence of subclinical hypothyroidism (SCH) in patients with obesity. It is unclear if this biochemical abnormality may be a secondary phenomenon of obesity or a real hypothyroid state.
methodsA retrospective study of all the morbidly obese patients undergoing laparoscopic sleeve gastrectomy as bariatric procedure between October 2007 and November 2012 was performed. Weight loss, body mass index (BMI) and excess weight loss, baseline glucose, lipid profiles, and TSH levels were obtained before operation and postoperative determinations at 3, 6, and 12 months after surgery.
resultsSixty patients were included. Prevalence of subclinical hypothyroidism was 16.7% preoperatively, 10% at 3 months, 3.3% at 6 months, and 1.7% at 12 months. A significant correlation could be established between TSH decrease and weight loss at 12 months (Pearson 0.603; p = 0.007). TSH decrease showed a significant correlation with glucose and glycated hemoglobin decrease from 6th month onwards. Referring to lipid profile, an association of TSH decrease with total cholesterol, LDL cholesterol, or HDL cholesterol could not be determined. A significant association between TSH decrease and triglycerides and cardiovascular risk index triglycerides/HDL cholesterol reductions could also be established 12 months after surgery.
conclusionsSCH is usually corrected after bariatric surgery, while there are no significant changes in total or LDL cholesterol. This suggests that, in morbidly obese subjects, SCH is, in most patients, just a consequence of the abnormal fat accumulation and not a real hypothyroid state.
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