ArticleEuropean journal of clinical nutrition2014
Follow-up of bone mineral density and body composition in adolescents with restrictive anorexia nervosa: role of dual-energy X-ray absorptiometry.
Article in European journal of clinical nutrition, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- The Association between Weight Gain/Restoration and Bone Mineral Density in Adolescents with Anorexia Nervosa: A Systematic Review.Nutrients · 2016Pooled it
- Anorexia nervosa and body fat distribution: a systematic review.Nutrients · 2014Pooled it
- Adolescents with Low Body Mass Index Are More Vulnerable to Pediatric Nondisplaced Femoral Neck Fractures.Clinics in orthopedic surgery · 2025Article
- Bioelectrical Impedance Vector Analysis, Nutritional UltrasoundNutrients · 2024Article
- Observational
- The Significance of Dual-Energy X-ray Absorptiometry (DXA) Examination in Cushing's Syndrome-A Systematic Review.Diagnostics (Basel, Switzerland) · 2023Review
- Transition of young adults with metabolic bone diseases to adult care.Frontiers in endocrinology · 2023Review
- Bone Perspectives in Functional Hypothalamic Amenorrhoea: An Update and Future Avenues.Frontiers in endocrinology · 2022Review
- Current Applications and Selected Technical Details of Dual-Energy X-Ray Absorptiometry.Medical science monitor : international medical journal of experimental and clinical research · 2021Review
- Fat and bone: the multiperspective analysis of a close relationship.Quantitative imaging in medicine and surgery · 2020Review
- Anorexia Nervosa and Osteoporosis: Pathophysiology and Treatment.Journal of bone metabolism · 2019Review
- Assessment of nutritional status by dual X-Ray absorptiometry in women with rheumatoid arthritis: A case-control study.Medicine · 2019Observational
- Quantitative imaging techniques for the assessment of osteoporosis and sarcopenia.Quantitative imaging in medicine and surgery · 2018Review
- Assessment and clinical management of bone disease in adults with eating disorders: a review.Journal of eating disorders · 2017Review
- Bone Mineral Density after Weight Gain in 160 Patients with Anorexia Nervosa.Frontiers in nutrition · 2017Article
- Body composition in young female eating-disorder patients with severe weight loss and controls: evidence from the four-component model and evaluation of DXA.European journal of clinical nutrition · 2015Article
- Underweight, overweight, and pediatric bone fragility: impact and management.Current osteoporosis reports · 2014Review
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesRestrictive Anorexia nervosa (ANR) is an eating disorder (ED) characterized by a low bone mineral content (BMC) and by an alteration in body composition (reduction and abnormal distribution of fat mass-FM and lean mass-LM). The aim of our study was to address whether bone and body composition changes could be influenced by hormonal status and sport in female adolescents with restrictive anorexia nervosa-ANR. SUBJECTS/
methodsProspective study on 79 adolescents with ANR submitted to Dual Energy X-Ray Absorptiometry-DXA at baseline-T0 and after 12 months-T12. Among the 46/79-58.2% patients that completed the study, we evaluated total and regional FM and LM%, as well as lumbar bone mineral density (BMD) and Z-score, linking them to clinical variables: menarche/amenorrhea/hormonal therapy and physical activity.
resultsAt T0: body mass index (BMI)=16.4±1.4 kg/m2 with low levels of FM% (21.7±5.7) low BMC in 12/46-26.0% (mean Z-score: -1.21±1.27, with higher values related to physical activity-P=0.001). At T12: a significant increase in BMI-P=0.001, with LM reduction and FM increase (more evident in the trunk-P<0.001); regarding bone, no significant changes were observed, though a tendency in terms of improvement associated with resumption of menses.
conclusionsAfter 1 year, weight recovery was not associated with a reestablishment of bone values; by contrast, it was associated with an increase and a distortion in FM distribution, more evident in trunk region (potential and adjunctive risk factor for the relapse of the psychiatric condition). The complexity of these clinical findings suggested DXA, a low-dose and low-cost technique, in long-term monitoring of ANR patients.
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