ArticleDocumenta ophthalmologica. Advances in ophthalmology2014
Contributing factors to VEP grating acuity deficit and inter-ocular acuity difference in children with cerebral visual impairment.
Article in Documenta ophthalmologica. Advances in ophthalmology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- VEP estimation of visual acuity: a systematic review.Documenta ophthalmologica. Advances in ophthalmology · 2021Pooled it
- Vision Assessments and Interventions for Infants 0-2 Years at High Risk for Cerebral Palsy: A Systematic Review.Pediatric neurology · 2017Pooled it
- Article
- Visual Function and Neuropsychological Profile in Children with Cerebral Visual Impairment.Children (Basel, Switzerland) · 2022Article
- Contribution of objectively measured grating acuity by sweep visually evoked potentials to the diagnosis of unexplained visual loss.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022Article
- The Multidisciplinary Guidelines for Diagnosis and Referral in Cerebral Visual Impairment.Frontiers in human neuroscience · 2022Article
- Cerebral Visual Impairment Characterized by Abnormal Visual Orienting Behavior With Preserved Visual Cortical Activation.Investigative ophthalmology & visual science · 2021Article
- Cognitive, motor, and visual development in healthy children in the first 42 months of life.Arquivos brasileiros de oftalmologia · 2021Article
- Assessment of Human Visual Acuity Using Visual Evoked Potential: A Review.Sensors (Basel, Switzerland) · 2020Review
- Grating visual acuity impairment assessed by sweep visually evoked potentials in children with optic pathway tumors unable to perform optotype acuity tests.Arquivos brasileiros de oftalmologiaArticle
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Authors and funding
6 authors.
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Abstract
purposeTo investigate contributing factors to visual evoked potential (VEP) grating acuity deficit (GAD) and inter-ocular acuity difference (IAD) measured by sweep-VEPs in children with cerebral visual impairment (CVI).
methodsVEP GAD was calculated for the better acuity eye by subtracting acuity thresholds from mean normal VEP grating acuity according to norms from our own laboratory. Deficits were categorized as mild (0.17 ≤ deficit < 0.40 log units), moderate (0.40 ≤ deficit < 0.70 log units) or severe (deficit ≥0.70 log units). Maximum acceptable IAD was 0.10 log units.
resultsA group of 115 children (66 males-57 %) with ages ranging from 1.2 to 166.5 months (median = 17.7) was examined. VEP GAD ranged from 0.17 to 1.28 log units (mean = 0.68 ± 0.27; median = 0.71), and it was mild in 23 (20 %) children, moderate in 32 (28 %) and severe in 60 (52 %). Severe deficit was significantly associated with older age and anti-seizure drug therapy. IAD ranged from 0 to 0.49 log units (mean = 0.06 ± 0.08; median = 0.04) and was acceptable in 96 (83 %) children. Children with strabismus and nystagmus had IAD significantly larger compared to children with orthoposition.
conclusionIn a large cohort of children with CVI, variable severity of VEP GAD was found, with more than half of the children with severe deficits. Older children and those under anti-seizure therapy were at higher risk for larger deficits. Strabismus and nystagmus provided larger IADs. These results should be taken into account on the clinical management of children with this leading cause of bilateral visual impairment.
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