ArticleInvestigative ophthalmology & visual science2014
Vertical and oblique saccade disconjugacy in strabismus.
Article in Investigative ophthalmology & visual science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 30 citations in OpenAlex.
- Longitudinal Changes in Nystagmus Following Late Treatment for Congenital Blindness.Investigative ophthalmology & visual science · 2026Article
- Saccade-Related Activity in Superior Colliculus Predicts Eye Choice for Goal-Directed Saccades in Monkeys With Strabismus.Investigative ophthalmology & visual science · 2025Article
- Quantitative Assessment of Fixational Disparity Using a Binocular Eye-Tracking Technique in Children with Strabismus.Journal of eye movement research · 2025Article
- Disconjugacies of saccade duration and trajectories in strabismus.Strabismus · 2024Article
- Microstimulation of Interstitial Nucleus of Cajal Evokes Directionally Disconjugate Eye Movements in Monkeys With Pattern Strabismus.Investigative ophthalmology & visual science · 2022Article
- Reduced activity of vertically acting motoneurons during convergence.Journal of neurophysiology · 2022Article
- Abnormal Tuning in Nucleus Prepositus Hypoglossi of Monkeys With "A" Pattern Exotropia.Investigative ophthalmology & visual science · 2020Article
- Response Properties of Cells Within the Rostral Superior Colliculus of Strabismic Monkeys.Investigative ophthalmology & visual science · 2019Article
- Abnormal Eye Position Signals in Interstitial Nucleus of Cajal in Monkeys With "A" Pattern Strabismus.Investigative ophthalmology & visual science · 2019Article
- Article
- A Rhesus Monkey With a Naturally Occurring Impairment of Disparity Vergence. II. Abnormal Near Response Cell Activity in the Supraoculomotor Area.Investigative ophthalmology & visual science · 2019Article
- A Rhesus Monkey With a Naturally Occurring Impairment of Disparity Vergence. I. Behavioral Comparisons to Vergence in a Normal Animal.Investigative ophthalmology & visual science · 2019Article
- Activity of near-response cells during disconjugate saccades in strabismic monkeys.Journal of neurophysiology · 2018Article
- Comparison of three models of saccade disconjugacy in strabismus.Journal of neurophysiology · 2017Article
- Nonhuman Primate Studies to Advance Vision Science and Prevent Blindness.ILAR journal · 2017Review
- Neural mechanisms of oculomotor abnormalities in the infantile strabismus syndrome.Journal of neurophysiology · 2017Review
- Electrical stimulation of superior colliculus affects strabismus angle in monkey models for strabismus.Journal of neurophysiology · 2017Article
- Normal correspondence of tectal maps for saccadic eye movements in strabismus.Journal of neurophysiology · 2016Article
- Longitudinal Evaluation of Eye Misalignment and Eye Movements Following Surgical Correction of Strabismus in Monkeys.Investigative ophthalmology & visual science · 2016Article
- Strabismus and the Oculomotor System: Insights from Macaque Models.Annual review of vision science · 2016Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
purposePrevious studies have shown that horizontal saccades are disconjugate in humans and monkeys with strabismus. The present study was designed to extend these results to vertical and oblique saccades. A major goal was to assess the conjugacy in terms of both amplitude and direction.
methodsSaccadic eye movements were recorded binocularly in three adult monkeys. One had normal eye alignment, one had exotropia resulting from a bilateral medial rectus tenotomy in the first week of life, and one had esotropia resulting from prism rearing during the first 3 months of life. We assessed the conjugacy of saccades in various directions by comparing both amplitude and direction.
resultsSaccades in the strabismic monkeys were disconjugate in terms of both amplitude and direction. These effects were as large for vertical and oblique saccades as for horizontal ones. However, the pattern of disconjugacy often varied as a function of saccade direction. In some cases, saccades that appeared to be conjugate in terms of amplitude differed substantially when direction was taken into account.
conclusionsThese data indicate that the assessment of saccade disconjugacy in strabismus may yield misleading results if direction is not considered. The complex pattern of disconjugacy suggests that strabismus is associated with substantial abnormalities within the circuitry controlling saccades. Neurophysiological studies are needed to identify the specific neural substrates for these behavioral effects.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.