Evidence map›Paper›PMID 24345816›Full record

ArticleCancer epidemiology2014

Birth characteristics and risk of lymphoma in young children.

Erin L Marcotte, Beate Ritz, Myles Cockburn, Christina A Clarke, Julia E Heck

Open access · greenAbstract read
In one paragraph

Article in Cancer epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  5. Review
  6. Hispanic Ethnicity Differences in Birth Characteristics, Maternal Birthplace, and Risk of Early-Onset Hodgkin Lymphoma: A Population-Based Case-Control Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Erin L MarcotteDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, Box 951772, 650 Charles E. Young Drive, Los Angeles, CA 90095-1772, USA.
Beate RitzDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, Box 951772, 650 Charles E. Young Drive, Los Angeles, CA 90095-1772, USA.
Myles CockburnDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, MC 9175, Los Angeles, CA 90089-9175, USA.
Christina A ClarkeCancer Prevention Institute of California, 2201 Walnut Avenue, Suite 300, Fremont, CA 94538-2334, USA.
Julia E HeckDepartment of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, Box 951772, 650 Charles E. Young Drive, Los Angeles, CA 90095-1772, USA. Electronic address: jeheck@ucla.edu.
University of California, Los Angeles · USCancer Prevention Institute of California · USUniversity of Southern California · US

Funding

Translational Research Support CoreP30ES007048 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Joseph Leo Wiemels · 1996 to 2026
$46.4M
UCLA CANCER EPIDEMIOLOGY TRAINING PROGRAMT32CA009142 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHANG, ZUO-FENG · 1986 to 2024
$6.3M
Translational Pediatric Cancer Epidemiology Research Training GrantT32CA099936 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Logan G. Spector · 2004 to 2026
$5.1M
Air Pollution and Childhood Cancers in CaliforniaR21ES018960 · NIEHS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HECK, JULIA · 2010 to 2011
$421k
Pesticide Exposure and Childhood Cancer StudyR21ES019986 · NIEHS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI RITZ, BEATE R. · 2011 to 2012
$409k
NCI NIH HHS T32 CA009142NCI NIH HHS T32 CA09142NCI NIH HHS T32 CA099936NIEHS NIH HHS P30 ES007048NIEHS NIH HHS P30ES007048NIEHS NIH HHS R21 ES018960NIEHS NIH HHS R21ES018960NIEHS NIH HHS R21 ES019986NIEHS NIH HHS R21ES019986
6 · The paper itself

Abstract

backgroundLymphoma is the third most common childhood malignancy and comprises two types, Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL). The etiology of pediatric lymphomas is largely unknown, but has been suggested to have prenatal origins.

methodsIn this population-based study, California birth certificates were identified for 478 lymphoma cases diagnosed in children 0-5 years of age between 1988 and 2007; 208,015 controls frequency-matched by birth year were randomly selected from California birth records.

resultsCompared to non-Hispanic whites, Hispanic children had an increased risk of HL (odds ratio (OR) and 95% confidence interval (CI) 2.43 [1.14, 5.17]), and in particular, were diagnosed more often with the mixed cellularity subtype. For all types of lymphoma, we observed an about twofold risk increase with indicators for high risk pregnancies including tocolysis, fetopelvic disproportion and previous preterm birth. NHL risk doubled with the complication premature rupture of membranes (OR and 95% CI 2.18 [1.12, 4.25]) and HL with meconium staining of amniotic fluids (OR and 95% CI 2.55 [1.01, 6.43]).

conclusionThese data support previously reported associations between Hispanic ethnicity and HL and suggest that pregnancy related factors, such as intra-uterine infections and factors associated with preterm labor, may be involved in lymphoma pathogenesis.

Indexed as

AdultCaliforniaChild, PreschoolFemaleHispanic or LatinoHodgkin DiseaseHumansInfantInfant, NewbornLymphoma, Non-HodgkinMalePregnancyPregnancy ComplicationsPregnancy, High-RiskRegistriesRisk FactorsChildrenEpidemiologyHispanicsHodgkin LymphomaNon-Hodgkin lymphomaPregnancy

Identifiers

PMID24345816
PMCPMC4100477
OpenAlexW2024911212

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.