Evidence map›Paper›PMID 24345612›Full record

ReviewBiochimica et biophysica acta2014

Chromatin regulators of genomic imprinting.

Jamie R Weaver, Marisa S Bartolomei

Abstract readReview
In one paragraph

Review in Biochimica et biophysica acta, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 45 citations in OpenAlex.

  1. Novel Perspectives onEpigenomes · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Genomic Imprinting.Open access Macedonian journal of medical sciences · 2016
    Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Jamie R WeaverDepartment of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, 9-123 Smilow Center for Translational Research, Philadelphia, PA 19104, USA.
Marisa S BartolomeiDepartment of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, 9-123 Smilow Center for Translational Research, Philadelphia, PA 19104, USA. Electronic address: bartolom@mail.med.upenn.edu.
Translational Therapeutics (United States) · USUniversity of Pennsylvania · US

Funding

TRAINING PROGRAM IN CELL AND MOLECULAR BIOLOGYT32GM007229 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI BARTOLOMEI, MARISA S. · 1985 to 2023
$14.0M
SEQUENCES CONTROLLING H19 GENE IMPRINTINGR01GM051279 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI BARTOLOMEI, MARISA S. · 1994 to 2024
$5.1M
Sequences controlling H19 Gene ImprintingR37GM051279 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI BARTOLOMEI, MARISA S. · 2011 to 2020
$3.9M
Epigenetic Regulation of Imprinting in Mouse EmbryoR01HD042026 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI BARTOLOMEI, MARISA S. · 2002 to 2012
$3.5M
NICHD NIH HHS R01 HD042026NIGMS NIH HHS R01 GM051279NIGMS NIH HHS R37 GM051279NIGMS NIH HHS T32 GM007229
6 · The paper itself

Abstract

Genomic imprinting is an epigenetic phenomenon in which genes are expressed monoallelically in a parent-of-origin-specific manner. Each chromosome is imprinted with its parental identity. Here we will discuss the nature of this imprinting mark. DNA methylation has a well-established central role in imprinting, and the details of DNA methylation dynamics and the mechanisms that target it to imprinted loci are areas of active investigation. However, there is increasing evidence that DNA methylation is not solely responsible for imprinted expression. At the same time, there is growing appreciation for the contributions of post-translational histone modifications to the regulation of imprinting. The integration of our understanding of these two mechanisms is an important goal for the future of the imprinting field. This article is part of a Special Issue entitled: Chromatin and epigenetic regulation of animal development.

Indexed as

AnimalsChromatinChromatin Assembly and DisassemblyDNA MethylationGenomic ImprintingHumansChromatinDNA methylationEpigeneticsGenomic imprintingHistone modificationPolycomb

Identifiers

PMID24345612
PMCPMC3951659
OpenAlexW2079347510

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.