ArticleClinical biomechanics (Bristol, Avon)2014
In vivo loads in the lumbar L3-4 disc during a weight lifting extension.
Article in Clinical biomechanics (Bristol, Avon), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Advances in Musculoskeletal Modeling of the Thoraco-Lumbar Spine: A Comprehensive Systematic Review.Annals of biomedical engineering · 2025Pooled it
- Design Requirements for Annulus Fibrosus Repair: Review of Forces, Displacements, and Material Properties of the Intervertebral Disk and a Summary of Candidate Hydrogels for Repair.Journal of biomechanical engineering · 2016Pooled it
- Evaluating Interface Pressure Distribution and Range of Motion in a Mesh-Structure 3D-Printed Lumbar Brace.Bioengineering (Basel, Switzerland) · 2026Article
- Safety and accuracy of robot-assisted pedicle screw fixation: a randomized controlled trial.International journal of surgery (London, England) · 2025Article
- Optimisation of Intervertebral Disc Mechanical Properties and the Impact of Vertebral Alignment in Subject-Specific Finite Element Models.International journal for numerical methods in biomedical engineering · 2025Article
- In vivo kinematic study of lumbar center of rotation under different loads.BMC musculoskeletal disorders · 2025Article
- Biomechanical Study of Symmetric Bending and Lifting Behavior in Weightlifter with Lumbar L4-L5 Disc Herniation and Physiological Straightening Using Finite Element Simulation.Bioengineering (Basel, Switzerland) · 2024Article
- Is Advanced Age a Factor That Influences the Clinical Outcome of Single- or Double-Level MIS-TLIF? A Single-Center Study with a Minimum Two-Year Follow-Up on 103 Consecutive Cases.Life (Basel, Switzerland) · 2023Article
- Development and validation of a timely and representative finite element human spine model for biomechanical simulations.Scientific reports · 2020Article
- A Biomechanical Waist Comfort Model for Manual Material Lifting.International journal of environmental research and public health · 2020Article
- Article
- Off-axis response due to mechanical coupling across all six degrees of freedom in the human disc.JOR spine · 2019Article
- The effect of sitting posture on the loads at cervico-thoracic and lumbosacral joints.Technology and health care : official journal of the European Society for Engineering and Medicine · 2018Article
- A new dynamic six degrees of freedom disc-loading simulator allows to provoke disc damage and herniation.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2016Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundKnowledge of in vivo human lumbar loading is critical for understanding the lumbar function and for improving surgical treatments of lumbar pathology. Although numerous experimental measurements and computational simulations have been reported, non-invasive determination of in vivo spinal disc loads is still a challenge in biomedical engineering. The object of the study is to investigate the in vivo human lumbar disc loads using a subject-specific and kinematic driven finite element approach.
methodsThree dimensional lumbar spine models of three living subjects were created using MR images. Finite element model of the L3-4 disc was built for each subject. The endplate kinematics of the L3-4 segment of each subject during a dynamic weight lifting extension was determined using a dual fluoroscopic imaging technique. The endplate kinematics was used as displacement boundary conditions to calculate the in-vivo disc forces and moments during the weight lifting activity.
findingsDuring the weight lifting extension, the L3-4 disc experienced maximum shear load of about 230 N or 0.34 bodyweight at the flexion position and maximum compressive load of 1500 N or 2.28 bodyweight at the upright position. The disc experienced a primary flexion-extension moment during the motion which reached a maximum of 4.2 Nm at upright position with stretched arms holding the weight.
interpretationThis study provided quantitative data on in vivo disc loading that could help understand intrinsic biomechanics of the spine and improve surgical treatment of pathological discs using fusion or arthroplasty techniques.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.