Evidence map›Paper›PMID 24344986›Full record

SynthesisHPB : the official journal of the International Hepato Pancreato Biliary Association2014

Anticoagulation policy after venous resection with a pancreatectomy: a systematic review.

Manju D Chandrasegaram, Guy D Eslick, Wayne Lee, Mark E Brooke-Smith, Rob Padbury, Christopher S Worthley, John W Chen, John A Windsor

Open access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in HPB : the official journal of the International Hepato Pancreato Biliary Association, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. AnAnnals of hepato-biliary-pancreatic surgery · 2023
    Article
  8. Article
  9. Article
  10. Laparoscopic pancreatectomies for borderline tumors with major venous resections.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Observational
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Manju D ChandrasegaramHPB Department, Flinders Medical Centre, Adelaide, SA, Australia; Department of Surgery, The University of Sydney, Sydney Medical School, Nepean, Penrith, NSW, Australia.
Guy D Eslick
Wayne Lee
Mark E Brooke-Smith
Rob Padbury
Christopher S Worthley
John W Chen
John A Windsor
Flinders Medical Centre · AURoyal Adelaide Hospital · AUThe University of Sydney · AUAuckland City Hospital · NZThe University of Adelaide · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPortal vein (PV) resection is used increasingly in pancreatic resections. There is no agreed policy regarding anticoagulation.

methodsA systematic review was performed to compare studies with an anticoagulation policy (AC+) to no anticoagulation policy (AC-) after venous resection.

resultsThere were eight AC+ studies (n = 266) and five AC- studies (n = 95). The AC+ studies included aspirin, clopidogrel, heparin or warfarin. Only 50% of patients in the AC+ group received anticoagulation. There were more prosthetic grafts in the AC+ group (30 versus 2, Fisher's exact P < 0.001). The overall morbidity and mortality was similar in both groups. Early PV thrombosis (EPVT) was similar in the AC+ group and the AC- group (7%, versus 3%, Fisher's exact P = 0.270) and was associated with a high mortality (8/20, 40%). When prosthetic grafts were excluded there was no difference in the incidence of EPVT between both groups (1% vs 2%, Fisher's exact test P = 0.621).

conclusionThere is significant heterogeneity in the use of anticoagulation after PV resection. Overall morbidity, mortality and EPVT in both groups were similar. EPVT has a high associated mortality. While we have been unable to demonstrate a benefit for anticoagulation, the incidence of EPVT is low in the absence of prosthetic grafts.

Indexed as

Blood Vessel Prosthesis ImplantationPancreatectomyAnticoagulantsGuideline AdherenceHumansPortal VeinPostoperative HemorrhagePractice Guidelines as TopicRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeVenous ThrombosisAnticoagulants

Identifiers

PMID24344986
PMCPMC4113250
OpenAlexW1979367193

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.