Evidence map›Paper›PMID 24344902›Full record

ArticleThe journal of sexual medicine2014

Patient satisfaction with testosterone replacement therapies: the reasons behind the choices.

Jason R Kovac, Saneal Rajanahally, Ryan P Smith, Robert M Coward, Dolores J Lamb, Larry I Lipshultz

Abstract read
In one paragraph

Article in The journal of sexual medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Prevalence of secondary erythrocytosis in men receiving testosterone therapy A matched-cohort analysis of intranasal gel, injections, and pellets.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2023
    Article
  8. Article
  9. The Pre-Testosterone Therapy Checklist.The journal of sexual medicine · 2022
    Article
  10. Review
  11. Article
  12. The My-T study: Patient satisfaction and preference comparing topical and nasal testosterone therapies.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2019
    Article
  13. Article
  14. Erythrocytosis Following Testosterone Therapy.Sexual medicine reviews · 2018
    Review
  15. Article
  16. Article
  17. Article
  18. Is semen analysis necessary prior to the commencement of testosterone supplementation therapy in men of reproductive age?Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2014
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jason R KovacScott Department of Urology and the Center for Reproductive Medicine, Baylor College of Medicine, Houston, TX, USA.
Saneal Rajanahally
Ryan P Smith
Robert M Coward
Dolores J Lamb
Larry I Lipshultz

Funding

ZONA PELLUCIDA BINDING PROTEINS IN SPERM-EGG INTERACTIONSP01HD036289 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI LAMB, DOLORES JEAN · 2000 to 2010
$7.5M
Improving the Diagnosis of Congenital Genitourinary Defects.R01DK078121 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI LAMB, DOLORES JEAN · 2007 to 2021
$4.8M
K-12: Male Reproductive Health Research (MRHR) Career Development Program at BCMK12HD073917 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI LAMB, DOLORES JEAN · 2012 to 2016
$1.7M
NICHD NIH HHS K12 HD073917NICHD NIH HHS K12, HD073917-01NICHD NIH HHS P01 HD036289NICHD NIH HHS P01HD36289NIDDK NIH HHS 1R01DK078121NIDDK NIH HHS R01 DK078121
6 · The paper itself

Abstract

introductionTestosterone replacement therapy (TRT) for male hypogonadism is rapidly gaining popularity and acceptance. Options include gels, injections, and implantable subcutaneous pellets.

aimsThe aim of this study was to determine rates of patient satisfaction and reasons for patient preferences in hypogonadal men on TRT.

methodsAn anonymous, prospective survey was distributed to men presenting for TRT at an academic urology clinic. The survey was organized into multiple domains including patient satisfaction and treatment motivation.

main outcome measuresPatient satisfaction responses obtained via anonymous survey.

resultsAverage patient age was 49 ± 0.7 years (n = 382). Injectable testosterone was chosen by 53%, gel-based regimens by 31%, and pellets by 17%. Overall, 70% of patients were satisfied with their TRT and 14% reported dissatisfaction. Satisfaction rates were similar between gels (68%), injections (73%), and implantable pellets (70%). Doctor recommendation was the sole significant reason for patients preferring gel-based TRT (66% vs. 37% injection users vs. 31% pellet users). Injectable TRT was favored because of lower cost (35% vs. 21% gel users vs. 19% pellet users). Pellets were favored for ease of use (64% vs. 44% injection users vs. 43% gel users) and convenience (58% vs. 26% injection users vs. 19% gel users). Pellets had increased rates of satisfaction within the first 12 months. Improvements in concentration and mood occurred at higher percentages in satisfied patients.

conclusionsPatients are satisfied with TRT. Lower costs are important to patients on injections. Convenience and ease of use are central in choosing pellet therapy. Men on TRT should be questioned about mood and concentration because these factors exhibited the greatest improvements in satisfied patients.

Indexed as

Patient SatisfactionDrug ImplantsGelsHormone Replacement TherapyHumansHypogonadismMaleMiddle AgedProspective StudiesTestosteroneDrug ImplantsGelsTestosteroneMale HypogonadismPatient PreferencesPatient SatisfactionTestosterone Replacement Therapy

Identifiers

PMID24344902
PMCPMC3946859

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.